New Zealand white rabbit: a novel model for prolapse mesh implantation via a lumbar colpopexy

ConclusionsPolypropylene mesh negatively impacts VSM morphology and vaginal contractility in the rabbit, similar to the NHP, suggesting that the rabbit may serve as an alternative large-animal model. The vaginal thinning and appearance of a mesh exposure in the area of a mesh wrinkle suggest the rabbit may also serve as a model for understanding the pathophysiology of mesh exposure.
Source: International Urogynecology Journal - Category: OBGYN Source Type: research