Correction. Disabil Rehabil Assist Technol. 2019 Aug;14(6):643 Authors: PMID: 31322038 [PubMed - in process]
Source: Disability and Rehabilitation. Assistive Technology. - Category: Rehabilitation Tags: Disabil Rehabil Assist Technol Source Type: research

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Source: American Journal of Health Behavior - Category: Psychiatry & Psychology Authors: Source Type: research
Contributors : Tomassoni-Ardori Francesco ; Skyler Kuhn ; Vishal Koparde ; Lino TessarolloSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusBrain Derived Neurotrophic Factor (BDNF) is a potent modulator of brain synaptic plasticity. Signaling defects caused by dysregulation of its NTrk2 (TrkB) kinase (TrkB.FL) and truncated receptors (TrkB.T1) have been linked to the pathophysiology of several neurological and neurodegenerative disorders. We found that upregulation of Rbfox1, an RNA binding protein associated with intellectual disability, epilepsy and autism,  increases selectively...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
ConclusionsThese studies demonstrate child sleep problems are associated with poorer parent mental health and higher parenting stress.ImplicationsFuture longitudinal research including multiple measurements of child sleep problems and family functioning is required to clarify the directionality of associations. Such knowledge is key in adapting sleep interventions to better meet the needs of children with ADHD or ASD and their families.
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Publication date: Available online 22 August 2019Source: Stem Cell ResearchAuthor(s): Natascia Malerba, Patrizia Benzoni, Gabriella Maria Squeo, Raffaella Milanesi, Federica Giannetti, Lynette G. Sadleir, Gemma Poke, Bartolomeo Augello, Anna Irma Croce, Andrea Barbuti, Giuseppe MerlaAbstractGNB5 loss-of-function pathogenic variant cause IDDCA, a rare autosomal recessive human genetic disease characterized by infantile onset of intellectual disability, sinus bradycardia, hypotonia, visual abnormalities, and epilepsy. We generated a human induced pluripotent stem cells (hiPSCs) from skin fibroblasts of a patient with the hom...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Abstract PURPOSE: The aim of this study was to examine the prevalence of upper extremity musculoskeletal (MSK) diseases and to identify factors influencing disability among fruit tree farmers in Korea. MATERIALS AND METHODS: Of the 1150 subjects of the Namgaram study, 460 fruit tree farmers completed a questionnaire and underwent clinical evaluations, including physical assessments, laboratory tests, simple radiographic examinations, and magnetic resonance imaging studies of the upper extremities. Disability was assessed using the Disabilities of the Arm, Shoulder, and Hand outcome measure. Data were analyzed...
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
Generic and spine-specific surveys are used before surgery for lumbar degenerative spondylolisthesis (LDS) to measure pain. While both types of surveys can discern various aspects of pain, such as pain intensity and pain-associated disability, their ability to capture how pain impacts other outcomes, such as fulfillment of expectations, is not known.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Surgery is increasingly recommended for the treatment of degenerative cervical myelopathy (DCM) as it effectively halts neurological progression and improves functional impairment, disability and quality of life. Although neck pain is a common complaint in patients with DCM, high-quality, prospective studies that summarize the incidence and severity of preoperative pain and evaluate the impact of surgery on pain outcomes are scarce.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
The internal validity of long-term studies is significantly affected by the high loss to follow-up in the spine surgery population (>20%). Phone and email-based administration of patient-reported outcomes instruments is a less cumbersome approach for increasing response rates and assessment frequency while potentially decreasing follow-up burden on patients and physicians.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
Weinstein and Ponsetti demonstrated that despite increased pain, adults with previously unoperated adolescent idiopathic scoliosis (AIS) typically lead normal functioning lives. The Oswestry Disability Index (ODI) is a validated questionnaire for assessing back disability with 0-20 indicating minimal disability. A score of>30 has been used in past FDA trials as an inclusion criterion for surgical studies. We predict that increasing ODI scores will correlate with age, curve size, curve location and progression to surgery.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
In the current era of value-based health care reform, engaging patients in shared decision-making for treatment planning is imperative. Predictive models capable of providing individualized predictions of patient-reported outcomes (PROs) following cervical spine surgery have the potential to be valuable tools for a shared decision-making process.
Source: The Spine Journal - Category: Orthopaedics Authors: Source Type: research
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