Therapeutic targeting of GSK3{beta} enhances the Nrf2 antioxidant response and confers hepatic cytoprotection in hepatitis C

Conclusions
Inhibition of GSK3β exerts hepatoprotection in CHC possibly through its direct regulation of Nrf2 antioxidant response.

Source: Gut - December 8, 2014 Category: Gastroenterology Authors: Jiang, Y., Bao, H., Ge, Y., Tang, W., Cheng, D., Luo, K., Gong, G., Gong, R. Tags: Hepatology Source Type: research