Africa: Leishmaniasis Needs More Attention - It Causes Skin Lesions, and Can Kill

[The Conversation Africa] Leishmaniasis ranks on the World Health Organisation's list of neglected tropical diseases, along with the usual suspects such as dengue, chikungunya and rabies.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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Publication date: Available online 26 March 2020Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Wen-Hung Wang, Aspiro Nayim Urbina, Max R. Chang, Wanchai Assavalapsakul, Po-Liang Lu, Yen-Hsu Chen, Sheng-Fan Wang
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
CONCLUSIONS These findings indicate diffusion expansion, a unique spatial diffusion pattern of Zika, Chikungunya, and Dengue epidemics in Salvador-Bahia, namely. Knowing how and where arboviruses spread in Salvador-Bahia can help improve subsequent specific epidemic control interventions.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Abstract In Brazil, rabies occurs mainly within an urban cycle, in which dogs and bats are reservoirs. This paper aims to report the occurrence of rabies in Callithrix sp. in Niter ói, Rio de Janeiro, Brazil. In June 2019 a hybrid specimen was referred for diagnosis. The Direct Fluorescent Antibody, Mouse Inoculation, and Polymerase Chain Reaction tests were positive. A phylogenetic analysis was compatible with antigenic variant 3, characteristic of Desmodus rotundus. New stu dies should be undertaken to elucidate the real role of callitrichids in the urban rabies cycle.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Discussion Dengue is an important arboviral infection that affects about 40% of the world population. It is found mainly in topical and subtropical areas of the world mainly in developing countries but it range is spreading including the United States. A review of common arboviruses can be found here. It is a flaviavirus with 4 distinct serotypes named DENV-1 through DENV-4 and is spread by A. aegypti a day biting mosquito. Infection with one serotype confers immunity to that serotype but not the others. It does offer some protection for cross-infection but this only lasts a few months. Incubation period is 3-14 days with ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Abstract Being the largest archipelago country in the world, with a tropical climate and a unique flora and fauna, Indonesia habitats one of the most diverse biome in the world. These characteristics make Indonesia a popular travel destination, with tourism numbers increasing yearly. These characteristics also facilitate the transmission of zoonosis and provide ideal living and breading circumstances for arthropods, known vectors for viral diseases. A review of the past 10 years of literature, reports of the Ministry of Health, Republic of Indonesia and ProMED-mail shows a significant increase in dengue infection ...
Source: Critical Reviews in Microbiology - Category: Microbiology Authors: Tags: Crit Rev Microbiol Source Type: research
This article is part HuffPost’s Project Zero campaign, a yearlong series on neglected tropical diseases and efforts to eliminate them. More than 1 billion people on the planet suffer from illnesses that the world pays little attention to. Neglected tropical diseases are a group of at least 18 diseases that primarily affect people living in poverty in tropical regions of the world and are virtually unknown elsewhere, according to the World Health Organization. These are diseases like river blindness, which has infected 18 million people worldwide and caused blindness in 270,000 people; or...
Source: Science - The Huffington Post - Category: Science Source Type: news
Centers for Disease Control and Prevention. 09/06/2016 This 32-page health security report describes the work of the Centers for Disease Control and Prevention in 2015 to ensure Americans'health, safety, and security. It includes chapters on Public Health Preparedness and Response, Emerging and Zoonotic Infectious Diseases, and Global Health. It discusses the Ebola outbreak in West Africa, and outbreaks of chikungunya, dengue fever, foodborne illnesses, healthcare-associated infections, monkeypox, Rocky Mountain spotted fever, rabies, and plague. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: Global & Universal Authors: Source Type: news
Prior tumor cell studies have shown that the drugs sorafenib (Nexavar) and regorafenib (Stivarga) reduce expression of the chaperone GRP78. Sorafenib/regorafenib and the multi‐kinase inhibitor pazopanib (Votrient) interacted with sildenafil (Viagra) to further rapidly reduce GRP78 levels in eukaryotes and as single agents to reduce Dna K levels in prokaryotes. Similar data were obtained in tumor cells in vitro and in drug‐treated mice for: HSP70, mitochondrial HSP70, HSP60, HSP56, HSP40, HSP10, and cyclophilin A. Prolonged ‘rafenib/sildenafil treatment killed tumor cells and also rapidly decreased the expression ...
Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: Original Research Article Source Type: research
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Source: Journal of Cellular Physiology - Category: Cytology Authors: Tags: Original Research Article Source Type: research
This article reviews the current recommendations for pediatric travel immunizations, including specific travel vaccines such as typhoid, yellow fever, Japanese encephalitis virus, and rabies as well as prospective vaccines for significant global diseases like malaria, dengue, chikungunya, and Ebola. [Pediatr Ann. 2015;44(4):e89-e96.]. PMID: 25875985 [PubMed - in process]
Source: Pediatric Annals - Category: Pediatrics Authors: Tags: Pediatr Ann Source Type: research
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