KU Health will spend $39M-$45M on equipment for new cancer treatment

The University of Kansas Health System signed an agreement with global medical technology company IBA to buy a proton therapy system, which is a highly specialized form of radiation treatment that will be offered through the University of Kansas Cancer Center. The $39 million-$45 million contract includes the price for a ProteusONE unit and a long-term operation and maintenance agreement. KU Health anticipates breaking ground on a new proton therapy center to house the treatment system later this…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news

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Proton therapy has an important role in the management of head and neck cancer, where the dosimetric characteristics of proton particles are advantageous for treating tumors in complex anatomic areas. In addition to highly targeted dose depositions owing to the Bragg peak and superior lateral dose distribution of proton therapy, the introduction of spot-scanning techniques that allow intensity-modulated proton therapy (IMPT) further improve dose distributions and normal-tissue sparing relative to intensity-modulated (photon) radiation therapy (IMRT), a finding that has been validated in case-matched analyses showing lower ...
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research
Technical advances have made it possible to create highly conformal dose distributions using photon-based radiotherapy, prompting interest in hypofractionated radiotherapy. Prostate cancer shows higher fractionation sensitivity and a lower α/β ratio than healthy tissue; thus, the rationale is to use higher doses per fraction compared with conventional fractionation [1–3]. Randomized studies have shown that moderate hypofractionation was not inferior to conventional fractions [4–6], but they have not demonstrated the concept of b iological dose escalation i.e.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research
Removable dentures got stuck in a 72-year-old man's throat during surgery to...Read more on AuntMinnie.comRelated Reading: 3-month PET/CT helps track oropharyngeal cancer CBCT outstrips growth in all other dental x-ray segments US-guided core biopsy best for salivary gland tumors Intraoperative CT fine-tunes maxillofacial surgery Proton therapy helps oropharyngeal patients
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
The University of Texas M.D. Anderson Cancer Center is investing $159 million into an expansion project. M.D. Anderson will more than double the size of its Proton Therapy Center at 1840 Old Spanish Trail. The expansion will grow the center’s footprint to over 160,000 square feet, enough room for the cancer center to house eight proton therapy radiation machines developed by Japanese technology man ufacturer Hitachi, according to an Aug. 8 press release. The center currently spans 73,500 square…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
In conclusion, several influences on harmonization were identified: adherence/interpretation to/of the protocol, available technology, experience in treatment planning and use of different beam arrangements. In future, all OARs that should be included in the optimization need to be specified in order to further harmonize treatment planning. PMID: 31393203 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
To investigate the role of intensity-modulated proton therapy (IMPT) for regional nodal irradiation in patients with breast carcinoma in comparison with volumetric-modulated arc therapy (VMAT).
Source: Clinical Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research
In this study, we investigated the effectiveness of DAPT for enabling narrow-field treatment approaches. Material and methods: For five paranasal tumor patients, representing a wide patient spectrum, anatomically robust 4-field-star and narrow-field plans were calculated and their robustness to anatomical and setup uncertainties was compared with and without DAPT. Based on the nominal planning CTs, per patient up to 125 simulated CTs (simCTs) with different nasal cavity fillings were created and random translations and rotations due to patient setup uncertainties were further simulated. Plans were recalculated or re-optimi...
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
Conclusions: PT reduced the volumes of normal tissues exposed to radiation, particularly low-to-intermediate dose levels, and this was reflected in lower NTCP. Of the included endpoints, substantial reductions in population medians were seen from the delivered PT plans for auditory complications, xerostomia, and risk of secondary cancers of the brain and salivary glands. PMID: 31364899 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
trois centres français Abstract Intensity-modulated radiation therapy (IMRT) is presently the recommended technique for the treatment of locally advanced head and neck carcinomas. Proton therapy would allow to reduce the volume of irradiated normal tissue and, thus, to decrease the risk of late dysphagia, xerostomia, dysgeusia and hypothyroidism. An exhaustive research was performed with the search engine PubMed by focusing on the papers about the physical difficulties that slow down use of proton therapy for head and neck carcinomas. Range uncertainties in proton therapy (±3 %) paradoxically li...
Source: Cancer Radiotherapie - Category: Cancer & Oncology Authors: Tags: Cancer Radiother Source Type: research
CONCLUSION: If MC is more accurate than PB as reported in the literature, dosimetric and radiobiological results from the current study suggest that PB overestimates the target dose, EUD, and TCP for IMPT breast cancer treatment. The overestimation of dosimetric and radiobiological results of the target volume by PB needs to be further interpreted in terms of clinical outcome. PMID: 31343826 [PubMed - as supplied by publisher]
Source: Journal of Applied Clinical Medical Physics - Category: Physics Authors: Tags: J Appl Clin Med Phys Source Type: research
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