Men need breast cancer screening too
Men at increased risk for breast cancer need regular screening mammography...Read more on AuntMinnie.comRelated Reading: SBI: Don't overlook men when it comes to breast cancer FDG-PET/CT helps stage men with breast cancer, too Male breast masses require careful investigation Mammography, US help diagnose male breast cancer US is best bet in male breast, but only if imaging is absolutely necessary
PMID: 31405432 [PubMed - in process]
We report a 76-year-old patient who was diagnosed with concurrent accessory breast and primary lung cancer, both were positive for somatic BRCA-2 (E1593D) mutation. He received concurrent radiation and platinum-based chemotherapy for lung cancer with good response, but breast cancer progressed in about 8 months, and further progressed after single agent anastrozole in 10 months. Next Generation Sequencing (NGS) of breast cancer was also positive forCCND1 (Cyclin D1) and FGFR1 amplifications. Despite a poor molecular profile of breast cancer, and progression following platinum-based chemotherapy and anastrozole, he was succ...
AbstractAlterations inBRCA2,PALB2,CHEK2, andp53 genes have been identified for their association with male breast cancer in various studies. The incidence of male breast cancer in India is consistent with its global rate. The present study was carried out with an aim to evaluate the genetic alterations in male breast cancer patients from Malwa region of Punjab, India. Four male breast cancer patients belonging to different families were recruited from Guru Gobind Singh Medical College and Hospital, Faridkot, India. A total of 51 genes reported with implications in the pathogenesis of breast cancer were screened using next ...
Conclusion: The competing risk nomogram showed good accuracy for predictive prognosis in nonmetastatic MBC patients. It was a useful implement to evaluate crude mortalities of BCSD and OCSD, and help clinicians to choose appropriate therapeutic plans.
Though it's thought of as a disease that strikes women, men also battle breast cancer. "Men have breast tissue. I think that's an important lesson," says Dr. Kathryn Ruddy, medical oncologist and director of Mayo Clinic's Cancer Survivorship Program. "If a man finds an abnormality in his breast tissue, he should seek prompt medical attention." In [...]
In conclusion, mammary tumorigenesis caused bone loss in MMTV-PyMT mice. However, dietary supplementation with MSeA did not attenuate mammary tumor-associated bone loss in this model of male breast cancer. PMID: 31187394 [PubMed - as supplied by publisher]
Conclusions: 18F-FDG PET/CT is useful and should be considered for staging male patients with breast cancer especially suspected axillary or distant metastases. Further evaluation with higher number of patients is needed for comparison with pathology results and demonstrating the impact on treatment or survival.
ConclusionsThe purpose of GM assessment should be the detection of underlying pathological conditions, reversible causes (administration/abuse of aggravating substances), and the discrimination from other breast lumps, particularly breast cancer. Assessment should comprise a thorough medical history and physical examination of the breast and genitalia (including testicular ultrasound). A set of laboratory investigations may integrate the evaluation: testosterone (T), estradiol (E2), sex hormone ‐binding globulin (SHBG), luteinizing hormone (LH), follicular stimulating hormone (FSH), thyroid stimulating hormone (TSH), pro...
In conclusion, we have successfully established an effective nomogram to predict BCSS in MBC patients, which can assist clinicians in determining the appropriate therapy strategies for individual male patients.