The structure, specificity and function of anti-citrullinated protein antibodies

Nature Reviews Rheumatology, Published online: 28 June 2019; doi:10.1038/s41584-019-0244-4In this Perspectives article, the authors present how various types of anti-citrullinated protein antibodies (ACPAs) differ based on the structural interactions of these antibodies with their citrullinated antigens, and examine the potential consequences for ACPA-mediated effector functions.

Source: Nature Reviews Rheumatology - June 27, 2019 Category: Rheumatology Authors: Changrong Ge Rikard Holmdahl Source Type: research