OncoSec Receives Exclusive Licensing Rights from Dana-Farber Cancer Institute to CAR T-Cell Therapies for the Treatment of Solid Tumor Cancers

Development Collaboration Will Initially Focus on CAR T-Cell Therapy for Triple-Negative Breast Cancer SAN DIEGO and PENNINGTON, N.J., June 27, 2019 -- (Healthcare Sales &Marketing Network) -- OncoSec Medical Incorporated (OncoSec) (NASDAQ:ONCS), a co... Biopharmaceuticals, Oncology, Licensing OncoSec Medical, CAR T-cell, CAR T-cell therapies
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news

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Publication date: Available online 17 August 2019Source: Revista Clínica Española (English Edition)Author(s): J. Masip, J.R. Germà LluchAbstractRecent epidemiological studies have shown that alcohol consumption can increase the risk of arterial hypertension, atrial fibrillation and gastrointestinal and breast cancer. Various sectors are therefore promoting abstinence from alcohol. However, light alcohol consumption has once again been shown to reduce the risk of myocardial infarction and diabetes but with an unclear effect on cerebrovascular disease. The decision to consume alcohol should therefore be ...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research
ConclusionIn this study, we found that over-expression of TINCR may influence the tumor size and contribute to the poor prognosis of cancer.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
In conclusion, our data show how oncogenic and tumor-suppressive drivers of cellular senescence act to regulate surveillance processes that can be circumvented to enable SnCs to elude immune recognition but can be reversed by cell surface-targeted interventions to purge the SnCs that persist in vitro and in patients. Since eliminating SnCs can prevent tumor progression, delay the onset of degenerative diseases, and restore fitness; since NKG2D-Ls are not widely expressed in healthy human tissues and NKG2D-L shedding is an evasion mechanism also employed by tumor cells; and since increasing numbers of B cells express NKG2D ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Series Type : Expression profiling by high throughput sequencing ; Genome binding/occupancy profiling by high throughput sequencingOrganism :This SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing Source Type: research
Contributors : Qing-Lan Li ; Dan-Ya Wang ; Lin-Gao Ju ; Chuan Gao ; Pin-Ji Lei ; Lian-Yun Li ; Xiao-Lu Zhao ; Min WuSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism :Activation of transcription enhancers, especially super enhancers, is one of the important epigenetic features of tumorigenesis. However, only very few studies reported how the enhancer landscape evolves during tumorigensis. Here we utilized a proteomics approach and found that H3K27ac and H4K8ac are elevated in the mammary tumor of MMTV-PyVT mouse model, which was then confirmed by IHC results in human BRCA chips. ChIP-se...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Source Type: research
Contributors : Qing-Lan Li ; Dan-Ya Wang ; Lin-Gao Ju ; Chuan Gao ; Pin-Ji Lei ; Lian-Yun Li ; Xiao-Lu Zhao ; Min WuSeries Type : Expression profiling by high throughput sequencingOrganism :Activation of transcription enhancers, especially super enhancers, is one of the important epigenetic features of tumorigenesis. However, only very few studies reported how the enhancer landscape evolves during tumorigensis. Here we utilized a proteomics approach and found that H3K27ac and H4K8ac are elevated in the mammary tumor of MMTV-PyVT mouse model, which was then confirmed by IHC results in human BRCA chips. ChIP-seq studies reve...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Source Type: research
Publication date: December 2019Source: Materials Science and Engineering: C, Volume 105Author(s): Rebeca T. Steipel, Matthew D. Gallovic, Cole J. Batty, Eric M. Bachelder, Kristy M. AinslieAbstractAlso known as electrospray, electrohydrodynamic atomization has been used extensively in the last 15 years to develop polymer-based particles for drug delivery in cell and animal models. More recently, novel core-shell, multi-axial, and other electrospray particles have been developed from an array of polymers for a variety of biomedical applications. This review focuses on electrospray as a novel method of particle fabrication...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Publication date: Available online 16 August 2019Source: Diagnostic and Interventional ImagingAuthor(s): C. Mandoul, C. Verheyden, I. Millet, C. Orliac, E. Pages, I. Thomassin, P. TaourelAbstractDigital breast tomosynthesis (DBT) is a new imaging technology that addresses the limitation caused by overlapping structures in conventional two-dimensional digital mammography owing to the acquisition of a series of low-dose projection images. This unique technique provides a dual benefit to patients screened for breast cancer. First, DBT increases the cancer detection rate mostly by highlighting architectural distortions and all...
Source: Diagnostic and Interventional Imaging - Category: Radiology Source Type: research
In conclusion, our study demonstrated that USP14 regulated the cell cycle of breast cancer cells by regulating the ubiquitination of CyclinB1, which will provide a solid theoretical basis for the development of anti-cancer drugs targeting USP14.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
ConclusionTAM treatment does not seem to be associated with a higher rate of endometrial cancer in women with breast cancer compared to women treated with AIs or no treatment.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
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