Differences in coagulopathy and massive transfusion strategy based on trauma type

Trauma is the sixth most common cause of mortality worldwide but is the most common cause of death in individuals under 35  years of age [1]. In trauma patients, hemorrhage (exsanguinating) is responsible for 30%–40% of all deaths, especially within 6 h of arrival [2] and mortality among trauma patients requiring massive transfusion (MT) for exsanguinating hemorrhage is>50% [3]. Exsanguinating hemorrhage is associated with trauma-induced coagulopathy, and both coagulopathy and hemorrhage contribute to trauma –associated mortality [4,5].

Source: The American Journal of Emergency Medicine - June 24, 2019 Category: Emergency Medicine Authors: Kota Hoshino, Mamiko Naito, Yoshihiko Nakamura, Yuhei Irie, Takeshi Nishida, Taisuke Kitamura, Hiroyasu Ishikura Source Type: research