Deficient amygdala habituation to threatening stimuli in borderline personality disorder relates to adverse childhood experiences

Heightened amygdala response to threatening cues has been repeatedly observed in borderline personality disorder (BPD). A previous report linked hyperactivation to deficient amygdala habituation to repeated stimuli, but the biological underpinnings are incompletely understood.

Source: Biological Psychiatry - June 18, 2019 Category: Psychiatry Authors: Edda Bilek, Marlena L. Itz, Gabriela St ößel, Ren Ma, Oksana Berhe, Laura Clement, Zhenxiang Zang, Lydia Robnik, Michael M. Plichta, Corinne Neukel, Christian Schmahl, Peter Kirsch, Andreas Meyer-Lindenberg, Heike Tost Tags: Archival Report Source Type: research