Effect of Electron-donating / Withdrawing Substituents on the Fluorescence of Aniline Containing Fluorescein Schiff base Derivatives

Publication date: Available online 15 June 2019Source: Journal of Photochemistry and Photobiology A: ChemistryAuthor(s): Jinxia Xu, Fanyong Yan, Xiaodong Sun, Zhaoxu WangAbstractTwo Schiff bases fluorescence sensors (FP1 and FP2) based on fluorescein-monoaldehyde derivatives were designed, synthesized and characterized. The effect of electron-donating and electron-withdrawing substituents on fluorescence of fluorescein was investigated. Through the calculation of the frontier orbital, it is proved that when the probe coexists with Cu2+, the complex system is more stable and easier to form. The FP1 was used as effective fluorescent contrast agent for determining Cu2+ from 0 – 55 μM with the limit of detection of 0.23 μM in several real water samples, sensing membranes and intracellular imaging.Graphical abstractSchematic presentation of FP1 for the detection of Cu2+

Source: Journal of Photochemistry and Photobiology A: Chemistry - June 15, 2019 Category: Chemistry Source Type: research