Relationship between structural damage with loss of strength and functional disability in psoriatic arthritis patients

In patients with PsA involving the hands, structural alterations of the dominant hand assessed by conventional x-ray and ultrasound are associated with loss of strength measured objectively with dynamometry and greater disability also studied subjectively using the HAQ.
Source: Clinical Biomechanics - Category: Orthopaedics Authors: Source Type: research

Related Links:

Objective The aim of this study was to compare the effect of biologic agents and conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) on the psychologic status of patients with psoriatic arthritis (PsA) in remission or with low disease activity. Methods This is a case-control study of PsA patients in remission or with low disease activity treated at a single-center combined rheumatologic-dermatologic clinic between 2015 and 2017. Patients were assigned to 2 comparison groups according to their treatment (1) biologic drugs and (2) csDMARDs therapy. Psoriatic arthritis disease activity was evaluated b...
Source: JCR: Journal of Clinical Rheumatology - Category: Rheumatology Tags: Original Articles Source Type: research
Previous research to describe the impact of foot involvement in psoriatic arthritis has used the Leeds Foot Impact Scale in Rheumatoid Arthritis (LFIS-RA) in the current absence of any psoriatic arthritis foot...
Source: Journal of Foot and Ankle Research - Category: Podiatry Authors: Tags: Research Source Type: research
AbstractIntroductionThe aim of this study was to evaluate the impact of comorbidities on disease activity, patient ’s impact of the disease, patient global assessment, and function in psoriatic arthritis (PsA).MethodsConsecutive PsA patients were enrolled in this cross-sectional study. During the visit, the patients underwent a complete physical examination and clinical/laboratory data were collected, including type and number of comorbidities, recorded as simple comorbidity count (SCC).Disease activity was assessed using the Disease Activity Score for Psoriatic Arthritis (DAPSA) and the Minimal Disease Activity (MDA...
Source: Rheumatology and Therapy - Category: Rheumatology Source Type: research
Authors: Lanna C, Cesaroni GM, Mazzilli S, Vollono L, Gaziano R, Marino D, Bianchi L, Campione E Abstract Psoriasis, Psoriatic Arthritis and Nail psoriasis are chronic diseases that share a common underlying etiology of immunity dysregulation, enhanced activation of inflammatory pathways and remitting-relapsing course. Although nails represent a small percentage of the body surface involvement of this site can lead to impaired quality of life, severe discomfort and even result in permanent disability.Current therapeutic options for nail psoriasis include a variety of topical and systemic treatments although they ar...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
ConclusionsThe Turkish version of the SiPAS questionnaire is a simple useful, time ‐saving and valid tool for screening PsA in patients diagnosed with PsO with its high sensitivity and specificity. A SiPAS score ≥3 is an indication for referral to a rheumatologist.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
CONCLUSIONS: Patients treated with IXE versus PBO achieved significantly greater improvements and showed faster onset of improvements in patient-reported outcomes measuring symptoms and impact of PsA. Responses were sustained over 2 years and were generally consistent regardless of prior TNFi experience. PMID: 32573426 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: Francesco B, Paolo G, Giampiero G Abstract INTRODUCTION: Psoriatic arthritis (PsA) is chronic inflammatory disease associated with psoriasis in 20-30% of patients. PsA presents as a heterogeneous disease involving different domains and burdened by an important impact on function and quality of life.Areas covered: Dermatologists play an important role in the early detection of PsA because in most patients PsA develop after cutaneous psoriasis. The ideal goal of treating patients with PsA is to optimize the controls of symptoms, improve quality of life, and prevent structural damage and disability. The choic...
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
ConclusionsThe prevalence and impact of medical comorbidity on PROs are very high in patients with PsA.
Source: Rheumatology and Therapy - Category: Rheumatology Source Type: research
ConclusionA concise overview on drug-drug interactions is given. Especially in more sophisticated cases extensive knowledge of drug interactions supports optimisation of therapy and results in improved patient safety.
Source: Rheumatology International - Category: Rheumatology Source Type: research
CONCLUSION: Through discussion and Delphi exercises, we achieved consensus to prioritize six physical function PROMs for PsA. These six PROMs will undergo further appraisal using the Outcome Measures in Rheumatology (OMERACT) Filter 2.1. PMID: 32007934 [PubMed - as supplied by publisher]
Source: J Rheumatol - Category: Rheumatology Authors: Tags: J Rheumatol Source Type: research
More News: Arthritis | Disability | Orthopaedics | Psoriatic Arthritis | Rheumatology | Ultrasound