Flu patients use artificial lungs to heal

TORONTO, Jan. 27 (UPI) -- Toronto General Hospital physicians say they used Extra Corporeal Lung Support -- artificial lungs -- to aid the recovery of five influenza patients.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Conclusion: Acalabrutinib monotherapy produced high response rates and demonstrated an acceptable safety profile in patients with TN CLL.DisclosuresFurman: Gilead: Consultancy; Loxo Oncology: Consultancy; Acerta: Consultancy, Research Funding; Genentech: Consultancy; Pharmacyclics LLC, an AbbVie Company: Consultancy; Sunesis: Consultancy; TG Therapeutics: Consultancy; Verastem: Consultancy; Incyte: Consultancy, Other: DSMB; Janssen: Consultancy; AbbVie: Consultancy. Martin: Gilead: Consultancy; Janssen: Consultancy; Bayer: Consultancy; Seattle Genetics: Consultancy; AstraZeneca: Consultancy; Kite: Consultancy. O'Brien: Jan...
Source: Blood - Category: Hematology Authors: Tags: 642. CLL: Therapy, excluding Transplantation: Advances in Frontline Therapy of CLL Source Type: research
We present preliminary efficacy, safety, and pharmacodynamic results from an ongoing single-center, open-label, phase 2 study of acalabrutinib monotherapy in patients with R/R and high-risk, TN CLL.Methods: Patients with R/R or high-risk (chromosome 17p deletion [del17p] or mutation in TP53 or NOTCH1) TN CLL/small lymphocytic lymphoma (SLL) who met International Workshop on Chronic Lymphocytic Leukemia (IWCLL) 2008 criteria for treatment and had an Eastern Cooperative Oncology Group performance status ≤2 were eligible. Patients who had prior BTK inhibitor therapy were excluded. Patients were randomized to receive oral a...
Source: Blood - Category: Hematology Authors: Tags: 642. CLL: Therapy, excluding Transplantation: Poster III Source Type: research
Influenza is a significant cause of morbidity and mortality following lung transplant. We employ trivalent vaccination as per National Policy in our centre. The trivalent inactivated vaccine (TIV) is not protective against the 2017-18 circulating stain of Influenza B.We reviewed the outcomes in 221 lung transplants recipients post vaccination.All Patients are subject to influenza surveillance. Data include viral swabs, severity of symptoms, history of vaccination, immunosuppression and outcomes for lung transplant patients from November 2017 to date.Ten patients have Influenza DNA detection of which 2 Influenza A and 8 Inf...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Transplantation Source Type: research
Background: The correct management of immunosuppressed patients with pneumonia is debated. We evaluate prevalence, risk factors and characteristics of immunosuppressed patients coming from the community with pneumoniaMethods: A secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia hospitalized in 222 hospitals in 54 countries worldwide was conducted. Risk factors for immunosuppression included: AIDS, aplastic anemia, asplenia, hematological malignancy, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroids use and solid tu...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
Respiratory tract infections remain an important source of morbidity and mortality with pneumonia and influenza serving as the eighth leading cause of death in the United States and the number one cause of death from infectious diseases. Advances in medicine have led to more complex patient populations than in the past, with the advent of novel chemotherapies, immune modulating interventions, and transplantation all creating unique types of immune impairment. Our understanding of the pathogenesis of lung infections had led to the possibility of a uniquely personalized approach to each patient, recognizing the specific path...
Source: Clinics in Chest Medicine - Category: Respiratory Medicine Authors: Tags: Preface Source Type: research
This report shows that unexpected native lung recovery is possible even after prolonged loss of lung function an d that a previous healthy lung can recover from apparent irreversible lung injury.
Source: Journal of Artificial Organs - Category: Transplant Surgery Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Mesenchymal stem cell therapies fairly reliably reduce chronic inflammation for some period of time following the transplantation of cells. The cells don't survive long in the patient, and this effect is mediated by the signals they produce while present. Chronic inflammation causes many issues, including a disruption of tissue maintenance and regeneration. It contributes directly to the progression of numerous age-related conditions, including the components of frailty syndrome, but it is an open question as to the degree to which it is required to maintain the current state of those conditions. If inflammation is suppres...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
This study found that professional chess players had shorter lifespans than those players who had careers outside of chess and argued that this might be due to the mental strain of international chess competition. In the present study, we focused on survival of International Chess Grandmasters (GMs) which represent players, of whom most are professional, at the highest level. In 2010, the overall life expectancy of GMs at the age of 30 years was 53.6 years, which is significantly greater than the overall weighted mean life expectancy of 45.9 years for the general population. In all three regions examined, mean life...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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