[Effects of mitochondrial aldehyde dehydrogenase 2 on autophagy-associated proteins in neonatal rat myocardial fibroblasts cultured in high glucose].

CONCLUSIONS: Mitochondrial ALDH2 inhibits the proliferation of neonatal rat cardiac fibroblasts induced by high glucose, and the effect is possibly mediated by the up-regulation of autophagy-related proteins Beclin-1 and LC3B.
PMID: 31140414 [PubMed - in process]

Source: Journal of Southern Medical University - May 29, 2019 Category: Universities & Medical Training Authors: Tang B, Kang P, Guo J, Zhu L, Xu Q, Gao Q, Zhang H, Wang H Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research