Impact of body fat and obesity on tissue dielectric constant (TDC) as a method to assess breast cancer treatment-related lymphedema (BCRL).

Impact of body fat and obesity on tissue dielectric constant (TDC) as a method to assess breast cancer treatment-related lymphedema (BCRL). Lymphology. 2019;52(1):18-24 Authors: Mayrovitz H Abstract Obesity is linked to the risk of breast cancer and treatment-related lymphedema (BCRL). Thus, knowledge of how obesity, or more specifically total body fat percentage (TBF) and body mass index (BMI), affect measurements that are used to detect or track lymphedema is clinically important. Tissue dielectric constant (TDC) is one measure used to help characterize lymphedema features, detect its presence, and assess treatment-related changes. The goal of this research was to determine the extent to which TDC values depend on TBF and BMI. TDC was measured on both forearms (2.5mm depth) in 250 women (18-72 years) along with TBF (impedance, 50KHz). TBF was 12.2%- 54.4% (median=29.3%) and BMI was 14.7Kg/m2-44.3 Kg/m2 (median=22.6 Kg/m2). TDC values and interarm ratios were compared between subgroups that had TBF and BMI values in lower vs. upper quartiles. Subjects in the upper quartile had slightly lower TDC values (1.3 TDC units, p
Source: Lymphology - Category: Internal Medicine Tags: Lymphology Source Type: research

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Conclusion: Our findings reveal that 10-wk synbiotic supplementation along with a LCD program-reduced serum MDA levels and elevate the activity of SOD in overweight and obese patients with BCRL. However, its effect on serum GPx, TAC, and edema volume was not significant. PMID: 31135225 [PubMed - as supplied by publisher]
Source: Nutrition and Cancer - Category: Cancer & Oncology Authors: Tags: Nutr Cancer Source Type: research
Abstract Breast cancer-related lymphedema (BCRL) is a potentially debilitating and often irreversible complication of breast cancer treatment. Risk of BCRL is proportional to the extent of axillary surgery and radiation. Other risk factors include obesity and infections. Given the 5-year survival rate of 90% and its potential impact on the quality of life of survivors of breast cancer, BCRL has become a significant financial burden on the health care system. Minimizing axillary surgery and radiation has been proven to reduce the risk of BCRL. Comprehensive multidisciplinary assessment at the time of initial diagno...
Source: JOP - Category: Gastroenterology Authors: Tags: J Oncol Pract Source Type: research
CONCLUSION: Angiosarcoma in lympedematous upper limbs or after breast cancer irradiation remains uncommon. However, its long latency and high mortality warrant long-term vigilant surveillance. PMID: 30738715 [PubMed - as supplied by publisher]
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: Clin Oncol (R Coll Radiol) Source Type: research
CONCLUSION: The results of this study offer valuable information on factors associated with adherence to a program of supervised and home-based exercise. Interventions may be adapted to ensure higher adherence rates through supportive efforts targeted to women who are obese, have low muscle strength and who receive no or adjuvant chemotherapy (as opposed to neoadjuvant chemotherapy) during exercise. PMID: 30698050 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
Lymphatic Research and Biology, Ahead of Print.
Source: Lymphatic Research and Biology - Category: Biology Authors: Source Type: research
CONCLUSIONS: Cumulative incidence of lymphedema was 41.1%. Women undergoing axillary radiotherapy, obese, who developed seroma, underwent chemotherapy infusion in the affected limb and with advanced disease had a higher risk of lymphedema. PMID: 28992556 [PubMed - as supplied by publisher]
Source: Breast - Category: Cancer & Oncology Authors: Tags: Breast Source Type: research
ConclusionsBCRL is a sequelae of multimodal breast cancer treatment and risk is multifactorial. BCRL rates are higher in patients receiving chemotherapy, radiation, ALND, more advanced disease stage, and higher body mass index.
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
CONCLUSIONSThe WISER Survivor Clinical Trial faced multiple recruitment challenges and used unique strategies to successfully enroll minority survivors of breast cancer into a lifestyle intervention. Cancer 2017. © 2017 American Cancer Society.
Source: Cancer - Category: Cancer & Oncology Authors: Tags: Original Article Source Type: research
We report on the innovative transdisciplinary design of this trial and report attrition rates.
Source: Contemporary Clinical Trials - Category: Radiology Authors: Source Type: research
Lymphedema has long been known as a life long complication from breast cancer surgery.I am not a doctor but here is my understanding of lymphedema: the lymph system is a second system in your body connecting hundreds of lymph nodes which help clean out your body and heal injuries or diseases. When you have surgery the lymph system is often impaired because it does not heal and reconnect after. If the lymph system is unconnected to the rest, you can end up with swollen body parts, or lymphedema.After breast cancer if a bunch of nodes are removed under your arm as with an axillary node dissection, you can end up with problem...
Source: Caroline's Breast Cancer Blog - Category: Cancer & Oncology Tags: lymph nodes lymphedema risks Source Type: blogs
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