Functional Status After Lung Transplantation in Older AdultsFunctional Status After Lung Transplantation in Older Adults
What has changed since the institution of the lung allocation score (LAS) system in 2005 -- for older recipients? American Journal of Transplantation
CRITICAL CARE CLINICS
Lung transplantation is the gold standard for treating patients with end-stage lung disease. Such patients can present with severe illness on the waitlist and may deteriorate before a lung donor is available. Bridging strategies with extracorporeal membrane oxygenation (ECMO) are valuable for getting patients to transplant and provide a chance at survival. The current article describes the indications, contraindications, and techniques involved in bridging to lung transplantation with ECMO.
ConclusionsOlder age, lower FEV1 % of predicted, and lower MEP were independently linked to unfavorable outcomes. FACED and BSI were not accurate in predicting mortality in our cohort.
Publication date: Available online 14 November 2018Source: The Annals of Thoracic SurgeryAuthor(s): Joshua Hsu, Aravind Krishnan, Cheng T. Lin, Pali D. Shah, Stephen R. Broderick, Robert S.D. Higgins, Christian A. Merlo, Errol L. BushAbstractBackgroundSarcopenia, a known component of frailty, defined by diminished cross-sectional area of the psoas muscles, is associated with poor outcomes after a range of surgical procedures. However, little is known of the relationship between sarcopenia of the psoas muscles (SPM) and long-term mortality, decline in pulmonary function, and graft failure after lung transplantation.MethodsW...
ConclusionsOur results suggest that even though donor and recipient age may be important in lung transplantation, the interplay between donor and recipient age alone is not an independent determinant of survival. Careful selection of lungs from donors over 60 years old should be exercised, taking into consideration the totality of donor demographics and risk factors rather than dismissing lungs based on advanced age alone
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ConclusionsMucormycosis involved mainly the sinu ‐orbital site and affected children>10 years. Despite aggressive treatment with high‐dose L‐AmB and timely surgical debridement, the mortality rate remains still high.