ask what is the best treatment for dengue fever

What Is the Best Treatment for Dengue Fever?
Source: - Category: General Medicine Source Type: news

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Last week, President Trumptweeted that Immigration and Customs Enforcement (ICE) agents were going to soon launch a major operation to arrest and deport illegal immigrants inside of the United States.   On Saturday, President Trump reversed himself and said that he is going todelay the operation.   TheWashington Examiner is now reporting that the operation is canceled permanently because acting Department of Homeland Security Secretary Kevin McAleenan leaked the details, thus removing the element of surprise and putting the “public at risk and law enforcement officers in harm ’s way” according t...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
Conclusions/SignificanceOur study confirms the protective effect of inspections on reported mosquito larval habitat reporting in households. Spatial, temporal and household-level characteristics should be accounted for in prioritizing vector control resources. Alternative strategies may help address recurrent entomological activity in households.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
More than 500 million people worldwide are infected each year by any of the four dengue virus (DENV) serotypes. The clinical spectrum caused during these infections is wide and some patients may develop neurological alterations during or after the infection, which could be explained by the cryptic neurotropic and neurovirulent features of flaviviruses like DENV. Using in vivo and in vitro models, researchers have demonstrated that DENV can affect the cells from the blood-brain barrier (BBB) in several ways, which could result in brain tissue damage, neuronal loss, glial activation, tissue inflammation and hemorrhages. The ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Dengue viruses cause severe and sudden human epidemics worldwide. The secreted form of the nonstructural protein 1 (sNS1) of dengue virus causes vascular leakage, a hallmark of severe dengue disease. Here, we reverse engineered the T164S mutation of NS1, associated with the severity of dengue epidemics in the Americas, into a dengue virus serotype 2 mildly infectious strain. The T164S mutant virus decreased infectious virus production and increased sNS1 production in mammalian cell lines and human peripheral blood mononuclear cells (PBMCs) without affecting viral RNA replication. Gene expression profiling of 268 inflammati...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Research Articles Source Type: research
K. Okada et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
In this study, we developed an enzyme-linked immunosorbent assay (ELISA) for the detection of dengue virus (DENV) NS1 by pairing a serotype-cross-reactive monoclonal antibody (MAb) with one of four serotype-specific MAbs in order to facilitate the rapid detection of NS1 antigens and the simultaneous differentiation of DENV serotypes. A total of 146 serum samples obtained from patients suspected to be in the acute phase of DENV infection were used to evaluate the clinical application of our novel test for the detection and serotyping of DENV. The overall sensitivity rate of our test was 84.85%, and the sensitivity rates for...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Virology Source Type: research
[East African] Four people have died in Tanzania as a result of the dengue fever and more than 4,000 others have been diagnosed with the disease, the government has said.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Abstract Antimicrobial peptides (AMPs), within their realm incorporate a diverse group of structurally and functionally varied peptides, playing crucial roles in innate immunity. Over the last few decades, the field of AMP has seen a huge upsurge, mainly owing to the generation of the so-called drug resistant 'superbugs' as well as limitations associated with the existing antimicrobial agents. Due to their resilient biological properties, AMPs can very well form the sustainable alternative for next-generation therapeutic agents. Certain drawbacks associated with existing AMPs are, however, issues of major concern,...
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research
de;o Maria de Fátima Vanderlei de Souza Helicteres velutina K. Schum (Sterculiaceae), a member of Malvaceae sensu lato, is a Brazilian endemic plant that has been used by the indigenous tribe Pankarare as an insect repellent. A previous study has reported the isolation of terpenoids, flavonoids and pheophytins, in addition to the larvicidal activity of crude H. velutina extracts derived from the aerial components (leaves, branches/twigs, and flowers). The present study reports the biomonitoring of the effects of fractions and isolated compounds derived from H. velutina against A. aegypti fourth instar larvae. ...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Publication date: Available online 20 June 2019Source: Journal of Theoretical BiologyAuthor(s): Abhishek Senapati, Tridip Sardar, Krishnendra Sankar Ganguly, Krishna Sankar Ganguly, Asis Kumar Chattopadhyay, Joydev ChattopadhyayAbstractDengue is one of the deadliest mosquito-borne disease prevalent mainly in tropical and sub-tropical regions. Controlling the spread of this disease becomes a major concern to the public health authority. World Health Organization (WHO) adopted several mosquito control strategies to reduce the disease prevalence. In this work, a general multi-patch non-autonomous dengue model is formulated to...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
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