Semiquantitative analysis of virtual histology derived from intravascular ultrasound images at vascular access stenosis.

Semiquantitative analysis of virtual histology derived from intravascular ultrasound images at vascular access stenosis. J Vasc Access. 2019 May;20(1_suppl):55-59 Authors: Sato T, Otsuka Y, Kikkawa Y, Iwasaki Y, Fukagawa M Abstract Vascular access failure, such as recurrent stenosis and thrombosis, is a major concern in patients with end-stage kidney disease. Neointimal hyperplasia development at the anastomosis site of outflow vessels is a primal cause for recurrent vascular access failure. We previously shed some lights into a role of vitamin D, which exerts a protective effect against neointimal hyperplasia formation. Virtual histology, derived from intravascular ultrasound technology, provides novel insights into plaque composition analysis in atherosclerotic diseases. However, there is so far a lack of evidence on the relation between virtual histology and pathophysiological findings. To elucidate this missing link, we comprehensively reviewed 10 chronic hemodialysis patients who underwent repeated intravascular ultrasound-guided balloon angioplasty. Their age, dialysis vintage, and follow-up period were 75.0 ± 4.24, 20.5 ± 2.12, and 11.5 ± 0.71 (mean ± standard deviation) years, respectively. Pathological cross-sectional analyses were performed using specimens from vascular access surgeries during the follow-up period. Interestingly, positive relation is found between virtual histology-constructed fibrous ti...
Source: The Journal of Vascular Access - Category: Surgery Tags: J Vasc Access Source Type: research