Hand, Foot, and Mouth Disease

Viral Immunology, Ahead of Print.
Source: Viral Immunology - Category: Allergy & Immunology Authors: Source Type: research

Related Links:

AbstractThe aim of this work is to reveal impacts of a nuclear power plant on environmental radioactivity and public health since commission in the South China Sea. After long-term monitoring, it turns out that radioactivity in ambient air environment, water, soil, sweet potato, rice, chicken, lamb, butterfish and prawn meet demands of national environment protection standards and food safety standards in China. After 6 years ’ statistic check of local residents, the top tree diseases before and after the plant’s commission remained pulmonary tuberculosis, hand-foot-and-mouth disease, and hepatitis B. Incidence...
Source: Journal of Radioanalytical and Nuclear Chemistry - Category: Nuclear Medicine Source Type: research
We report a case of reversible cerebral angiopathy after viral infection in a pediatric patient with genetic variant of RNF213 mutation. The patient had developed a severe headache after hand, foot, and mouth disease.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research
Hand, foot, and mouth disease (HFMD) raises an urgent public health issue in the Asia-Pacific region, especially in China. The associations between weather factors and HFMD have been widely studied but with in...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
The finding of reasonably consistent spatial and temporal productions of actions across different body parts has been used to argue in favor of the existence of a high-order representation of motor programs. In these terms, a generalized motor program consists of an abstract memory structure apt to specify a class of non-specific instructions used to guide a broad range of movements (e.g., “grasp,” “bite”). Although a number of studies, using a variety of tasks, have assessed the issue of effector independence in terms of action execution, little is known regarding the issue of effector independence...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
An unspecified, growing number of kindergartners and pre-kindergartners at Tse'hootsooi' Primary Learning Center in Window Rock, the capital of Navajo Nation, have contracted the disease in recent days.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
In this study, we investigated the antiviral effect of salvianolic acid B (SalB) on EV71. SalB is a major component of the Salvia miltiorrhiza root and has been shown to be an effective treatment for subarachnoid hemorrhages, and myocardial infarctions. HeLa cells were cultured in 12-well plates and treated with SalB (100 or 10 μg/mL) and 106 PFU/mL of EV71. SalB treatment (100 µg/mL) significantly decreased the cleavage of the eukaryotic eIF4G1 protein and reduced the expression of the EV71 capsid protein VP1. In addition, SalB treatment showed a dramatic decrease in viral infection, measured by immunofluorescenc...
Source: Journal of Microbiology and Biotechnology - Category: Biotechnology Authors: Tags: J Microbiol Biotechnol Source Type: research
In this study, the vp1 gene of Enterovirus 71 (EV71) and Coxsackievirus B3 (CB3) was inserted into the vector pET22b (+) to form the respective expression plasmids pEVP1 or pCVP1, and then transformed into Escherichia coli strain BL21 (DE3). The recombinant EVP1 or CVP1 protein was overexpressed successfully and effectively purified to homogeneity. Then, we identified that EVP1 and CVP1 protein could generate effectively specific humoral immunity and cellular immunity in mice, what's more, we determined the cross-protection of VP1 between EV71 and CB3 in a murine model. The results showed that immunization with EVP1 could ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conclusion: The study will provide evidence to judge whether probiotics is an effective therapeutic intervention for severe HFMD. PROSPERO registration number: PROSPERO CRD42019152946.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Abstract BACKGROUND: Coxsackievirus A6 (CA6) infection may lead to high hand-foot-and-mouth disease (HFMD) aggregation in children. We aimed to analyze the clinical and phylogenetic features of severe CA6-associated pediatric HFMD. METHODS: The clinical and laboratory features of 206 and 55 children with mild and severe CA6-associated HFMD, respectively, were summarized. The CA6 phylogenetic tree was depicted using combinatorial analysis of the VP1-encoding regions and neighbor-joining method. RESULTS: CA6 was the major pathogen both in mild and severe HFMD in 2017. Most CA6-associated severe HFMD cases ...
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research
This study provides valuable supplemental information to facilitate our understanding of the specific protective efficacy of CV-A16 VLPs and has significance for development of the candidate vaccine into a safe and effective vaccine.
Source: Archives of Virology - Category: Virology Source Type: research
More News: Allergy & Immunology | Hand, Foot and Mouth