Corneal keloid presenting forty years after penetrating injury: case report and literature review

A 64-year-old Caucasian man had been diagnosed with presumed ocular surface squamous neoplasia in the left eye and started on topical interferon alpha 2b drops. When we saw him, he provided a history of penetrating corneal injury more than forty years prior. Slit lamp examination revealed a large, elevated, opaque lesion involving the left cornea. High-definition AS-OCT revealed a hyper-reflective lesion involving the anterior stroma with a relatively normal overlying epithelium. Based on the clinical history, slit lamp, and AS-OCT findings, a giant corneal keloid was suspected, and the interferon drops were discontinued.

Source: Survey of Ophthalmology - March 4, 2019 Category: Opthalmology Authors: Joel R. Palko, Safa Arfeen, Asim V. Farooq, Catherine Reppa, George J. Harocopos Tags: Clinical Pathologic Reviews Source Type: research