Machine Learning Models Based on the Dimensionality Reduction of Standard Automated Perimetry Data for Glaucoma Diagnosis

ConclusionA glaucoma diagnosis model giving an AUC of 0.912 was constructed by applying machine learning techniques to SAP data. The results show that dimensionality reduction not only reduces dimensions of the input space but also enhances the classification performance. The variable selection results show that the proposed composite variables from visual field clustering play a key role in the diagnosis model.
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research

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Authors: Shubhakaran K PMID: 31315344 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: The expression of sFRP1 accelerates the aging process in mouse eyes and future studies are warranted to elucidate the underlying mechanisms. PMID: 31318361 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Conclusions: This is the first reported case of occlusive retinal vasculopathy subsequent to intravitreal administration of rituximab. Whereas hypersensitivity reactions to intravenous infusion of rituximab have been noted in the literature, no such reports exist in response to intravitreal therapy. PMID: 31314626 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
Conditions:   Glaucoma;   Ocular Hypertension Intervention:   Device: Goldfish (GF) Sponsor:   Sensimed AG Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension Interventions:   Drug: Brinzolamide 1% ophthalmic suspension;   Drug: Azopt 1% Ophthalmic Suspension Sponsor:   Perrigo Company Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma;   Ocular Hypertension Intervention:   Device: Goldfish (GF) Sponsor:   Sensimed AG Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension Interventions:   Drug: Brinzolamide 1% ophthalmic suspension;   Drug: Azopt 1% Ophthalmic Suspension Sponsor:   Perrigo Company Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma;   Ocular Hypertension Intervention:   Device: Goldfish (GF) Sponsor:   Sensimed AG Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension Interventions:   Drug: Brinzolamide 1% ophthalmic suspension;   Drug: Azopt 1% Ophthalmic Suspension Sponsor:   Perrigo Company Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Izquierdo Villavicencio JC, Agudelo Arbelaez N, Lastra BR, Ramirez I, Quezada F, Ponte MC, Cañola L, Mejias Smith J Abstract Purpose/Objective: To evaluate the effectiveness of combined phacoemulsification, viscogoniosynechialysis (VGSL), and endocyclophotocoagulation (ECP) in patients with moderate chronic angle-closure glaucoma (CACG) with peripheral anterior synechia (PAS) ≥90 not controlled with glaucoma medications and previous iridotomy yag laser. Materials and Methods: We retrospectively reviewed records from patients with cataract and uncontrolled chronic angle-closure glaucoma despit...
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
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