Acute non ‐heparin‐induced thrombocytopenia during hemodiafiltration in a patient with multiple myeloma

This report demonstrates that not only heparin ‐induced thrombocytopenia, but also hemodialysis conditions (platelet activation due to hemodiafiltration and heparin underdosing) may markedly reduce the platelet count and cause clotting in the hemodialysis circuit in patients in a hypercoagulable state. The clot prevention effects of bortezomib are therefore of great importance. Key Clinical MessageThis report demonstrates that not only heparin ‐induced thrombocytopenia, but also hemodialysis conditions (platelet activation due to hemodiafiltration and heparin underdosing) may markedly reduce the platelet count and cause clotting in the hemodialysis circuit in patients in a hypercoagulable state. The clot prevention effects of bortezomib are therefore of great importance.

Source: Clinical Case Reports - February 22, 2019 Category: General Medicine Authors: Makiko Morita, Kayoko Nakanishi, Kenta Masuda, Kazuhiro Yoshida, Daiki Shimomura, Atsumi Ishida, Shuichi Shiga, Satoshi Ichiyama Tags: CASE REPORT Source Type: research