Deep Learning-Enhanced Device Detects Diabetic Retinopathy

WEDNESDAY, Feb. 20, 2019 -- A deep learning-enhanced device can accurately detect diabetic retinopathy (DR), according to a study published online Feb. 14 in Diabetes Care. For people with type 2 diabetes visiting a primary care screening program,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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Authors: Draijer L, Benninga M, Koot B Abstract INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children and adults in industrialized countries. Besides liver-related morbidity, NAFLD is also associated with an increased risk of cardiovascular disease, type 2 diabetes and mortality at adult age. However, despite the high prevalence and serious complications, diagnosing and staging of disease remains complicated due to a lack of accurate screening tools and non-invasive methods to detect fibrosis. Areas covered: Recent insights in epidemiology, pathogenesis, diagno...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
Publication date: May 2019Source: Journal of Functional Foods, Volume 56Author(s): Suling Sun, Guowei Zhang, Hongyan Mu, Hao Zhang, Yong Q. ChenAbstractCorn peptide promotes glucagon-like peptide-1 release in type 2 diabetic animals, while wheat peptide increases pro-inflammatory cytokine response in type 1 diabetic patients. However, the effect of a mixture of corn and wheat peptide on the initiation and the development of type 1 diabtes remains unclear. Corn peptide reduced the blood glucose in wheat peptide-evoked diabetic NOD mice. A mixture of corn and wheat peptide significantly delayed the initiation and decreased t...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
ConclusionThe present study has evaluated 14 studies published during the year 2015–2018. Studies from Egypt, Iraq, Jordan, Oman, Qatar, Saudi Arabia, Tunisia, and United Arab Emirates had been explored studying the associations of GIPR, ADIPOQ, FTO, (GRCh38.p12), MLXIP, AKNAD1, KCNJ11 CDKAL1, CDKN2A/2B, TCF7L2, ACE, SNAP25, ELMO1, VDR, KCTD8, GABRA4 and PRKD1 genes with T2D development.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 15 March 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Thien Chu Dinh, Thuy Nguyen Thi Phuong, Le Bui Minh, Vu Thi Minh Thuc, Nguyen Duy Bac, Nguyen Van Tien, Van Huy Pham, Pau Loke Show, Yang Tao, Vo Truong Nhu Ngoc, Nguyen Thi Bich Ngoc, Adam Jurgoński, Deepak B. Thimiri Govinda Raj, Pham Van Tu, Vu Ngoc Ha, Joanna Czarzasta, Dinh-Toi ChuAbstractObesity is one of the top global issues, which induces several serious health consequences both physically and mentally, such as type 2 diabetes, cardiovascular diseases, dyslipidemia, eating disorders, ...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 16 March 2019Source: MethodsAuthor(s): Nathan LaPierre, Chelsea J.-T. Ju, Guangyu Zhou, Wei WangAbstractThe human microbiome plays a number of critical roles, impacting almost every aspect of human health and well-being. Conditions in the microbiome have been linked to a num-ber of significant diseases. Additionally, revolutions in sequencing technology have led to a rapid increase in publicly-available sequencing data. Consequently, there have been grow-ing efforts to predict disease status from metagenomic sequencing data, with a proliferation of new approaches in the last few years. So...
Source: Methods - Category: Molecular Biology Source Type: research
The headlines are once again filled with advice to reduce egg and cholesterol consumption based on a study that found an association of egg and cholesterol consumption with increased risk for cardiovascular events. Sounds scary and persuasive, doesn’t it? After all, nearly 30,000 people were tracked over 17 years and the authors authoritatively declare that this proves that eggs and cholesterol are risk factors for heart disease. There are several problems with this assessment. It is emblematic of the studies that confuse people, yield wildly conflicting conclusions, are used to craft absurd and ineffective dietary g...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates cholesterol eggs grain-free saturated fat undoctored wheat belly Source Type: blogs
Publication date: Available online 15 March 2019Source: Journal of Pharmacological SciencesAuthor(s): Sheng-gao Tang, Xiao-yu Liu, Shan-ping Wang, Hong-hui Wang, Aleksandar Jovanović, Wen TanAbstractDiabetic cardiomyopathy (DCM) is characterized by cardiac hypertrophy, fibrosis, oxidative stress and inflammation. Trimetazidine (TMZ), a potent metabolism modulator, has been shown to be cardioprotective in experimental models of ischaemia-reperfusion and type 2 diabetes-induced cardiomyopathy. The present study examined whether TMZ inhibits cardiomyopathy induced by insulin-dependent type 1 diabetes. Wistar rats were random...
Source: Journal of Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research
TYPE 2 diabetes can be controlled by cutting down on foods which are high in sugar, but this can be hard to do when so many foods, and especially breakfast options, contain lots of it. If you like a slice of toast in the morning, consider replacing jam with this tasty, but still sweet, spread to prevent high blood sugar.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Approximately 30% of patients undergoing heart transplantation (HTx) may have diabetes mellitus type 2 (DM2). More importantly, DM2 may become more prevalent after HTx because of high corticosteroid use. Metformin - an oral anti-hypoglycemic drug for DM2- has also been demonstrated to have immunomodulatory effects. It has been reported that metformin may decrease acute and chronic rejection as well as the development of cardiac allograft vasculopathy (CAV). Therefore, we reviewed our HTx patients placed on metformin pre-HTx and post-HTx to assess potential outcomes and benefits.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 678 Source Type: research
ConclusionsDiffusion kurtosis imaging detects more brain regions with white matter and gray matter microstructural alterations of T2DM patients than DTI metrics. It provides valuable information for studying the pathology of diabetic encephalopathy and may lead to better imaging biomarkers for monitoring disease progression.Key Points• Diffusion kurtosis imaging detects more brain regions with microstructural alterations in white matter and gray matter of T2DM patients than DTI.• Mean kurtosis changes are associated with disease severity and impaired neuropsychological function in T2DM.• Diffusion kurtosis i...
Source: European Radiology - Category: Radiology Source Type: research
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