Vaccine for Ebola closer as experimental drug ‘protects against ALL strains of the killer virus’

Scientists at The University of Texas Medical Branch said the drug could continue to protect people even as Ebola evolves. The efficiency could relieve burden on the frontline health care workers.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 20 May 2019Source: Biochimica et Biophysica Acta (BBA) - General SubjectsAuthor(s): Yasunori Watanabe, Thomas A. Bowden, Ian A. Wilson, Max CrispinAbstractGlycosylation is a ubiquitous post-translational modification responsible for a multitude of crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to glycosylate their own proteins during replication. Viral envelope proteins from a variety of human pathogens including HIV-1, influenza virus, Lassa virus, SARS, Zika virus, dengue virus, and Ebola virus have evolved to be extensively glycosylated. These host...
Source: Biochimica et Biophysica Acta (BBA) General Subjects - Category: Biochemistry Source Type: research
Publication date: Available online 16 May 2019Source: CellAuthor(s): Carl W. Davis, Katherine J.L. Jackson, Anita K. McElroy, Peter Halfmann, Jessica Huang, Chakravarthy Chennareddy, Ashley E. Piper, Yvonne Leung, César G. Albariño, Ian Crozier, Ali H. Ellebedy, John Sidney, Alessandro Sette, Tianwei Yu, Sandra C.A. Nielsen, Arthur J. Goff, Christina F. Spiropoulou, Erica Ollman Saphire, Guy Cavet, Yoshihiro KawaokaSummaryEbola virus (EBOV) remains a public health threat. We performed a longitudinal study of B cell responses to EBOV in four survivors of the 2014 West African outbreak. Infection induced lastin...
Source: Cell - Category: Cytology Source Type: research
[Thomson Reuters Foundation] New York -Documented attacks on health workers in conflict areas increased dramatically last year, endangering both children waiting for polio vaccines and efforts to contain the latest outbreak of Ebola, research showed on Wednesday.
Source: AllAfrica News: Polio - Category: Infectious Diseases Source Type: news
Source: Safeguarding Health in Conflict. Published: 5/15/2019. In 2018, the Safeguarding Health in Conflict Coalition documented 973 attacks on health care in 23 countries in conflict, which are discussed in this 35-page report. The report documents attacks against vaccination workers, paramedics, nurses, doctors, midwives, patients, community volunteers, and drivers and guards, in violation of longstanding human rights and humanitarian law norms to protect and respect health care in conflict. It discusses violence in the Democratic Republic of the Congo, which posed a great threat to containing the spread of the Ebola virus disease. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
May 14, 2019 WashingtonThere were at least 973 attacks on health workers, health facilities, health transports, and patients in 23 countries in conflict in 2018, the  Safeguarding Health in Conflict Coalition reported today. At least 167 health workers died and at least 710 were injured. This marks an increase in the number of documented attacks compared to 2017, when the coalition reported 701 such instances.The coalition ’s sixth annual report documents attacks on vaccination workers, paramedics, nurses, doctors, midwives, community volunteers, drivers, and guards, in violation of international norms an...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: Safeguarding Health in Conflict Coalition Policy & Advocacy Source Type: news
Following the April 2018 reemergence of Ebola in a rural region of the Democratic Republic of the Congo (DRC), the virus spread to an urban center by early May. Within 2 wk of the first case confirmation, a vaccination campaign was initiated in which 3,017 doses were administered to contacts...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
[WHO] Juba, 8 May 2017 - Alice Baku (not real name) a clinician at the Juba teaching hospital said "I am glad I was vaccinated against Ebola Virus disease because prevention is better than cure"
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
WHO ’s Strategic Advisory Group of Experts has issued new recommendations to address vaccination challenges in the ongoing Ebola outbreak in the Democratic Republic of the Congo.
Source: PharmaManufacturing.com - Category: Pharmaceuticals Source Type: news
As violence makes it harder to reach stricken villages in Congo, experts plan to stretch supplies and to give the vaccine to everyone, not just contacts of victims.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Ebola Virus Vaccination and Immunization Congo, Democratic Republic of (Congo-Kinshasa) Epidemics World Health Organization Johnson & Merck Company Inc Source Type: news
Publication date: Available online 7 May 2019Source: Microbial PathogenesisAuthor(s): Bilal Ahmad, Usman Ali Ashfaq, Mahmood-ur Rahman, Muhammad Shareef Masoud, Muhammad Zubair YousafAbstractEbola virus (EBOV), a non-segmented single-stranded RNA virus, is often-most transmitted through body fluids like sweat, tears, saliva, and nasal secretions. Till date, there is no licensed vaccine of EBOV is available in the market; however, the world is increasingly vulnerable to this emerging threat. Hence, it is the need of time to develop a vaccine for EBOV to hinder its dissemination. The current study has been designed for ident...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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