Cancer death rates decline, but economic gap remains

The overall cancer death rate in the U.S. dropped by 27% over the past 25 years,...Read more on AuntMinnie.comRelated Reading: Report predicts plunge in U.S. lung cancer mortality Cancer death disparities linked to poverty, lifestyle Global lung cancer death rates for women to increase Both screening, treatment cut breast cancer deaths Cancer deaths continue to fall, but CT lung screening lags
Source: Headlines - Category: Radiology Source Type: news

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This study describes a simple, economic, reproducible, and high-throughput assay to quantify cell death and proliferation. In this assay, adherent cells are fixed, stained with trypan blue, and measured for trypan blue internalization using a spectrophotometric absorbance plate reader. Corresponding cell counts to the absorbance measurements are extrapolated from a standard curve. This assay was used to measure the effect of dimethyl sulfoxide (DMSO) on the viability of breast and lung cancer cells. Decrease in cell count associated with the increase in DMSO percentage and exposure time. The assay ’s results closely ...
Source: Histochemistry and Cell Biology - Category: Biomedical Science Source Type: research
By analyzing tumor characteristics such as structure, shape, and size, an artificial...Read more on AuntMinnie.comRelated Reading: AI may predict lymph node metastasis in gastric cancer AI can predict breast cancer molecular subtypes on MRI Russian AI detects lung cancer on CT in 20 seconds AI can differentiate glioblastoma, brain metastasis AI uses features outside nodules to predict malignancy
Source: Headlines - Category: Radiology Source Type: news
Opinion statementIn the past, the standard of care for treatment of BM was whole brain radiation therapy (WBRT), stereotactic radiosurgery (SRS), and surgery. There has been a greater role for medical therapies in the last two decades due to the discovery of driver mutations and corresponding targeted therapies. These innovations have dramatically altered the approach to treating these patients. Some of the important mutations include epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) mutations in small cell lung cancer, human epidermal growth factor receptor (HER2) mutation in breast cancer, and ...
Source: Current Treatment Options in Oncology - Category: Cancer & Oncology Source Type: research
ConclusionIn this clinical practice setting, rivaroxaban was rarely used for cancer ‐associated VTE. However, among those who received rivaroxaban, the treatment appeared safe and effective with rates comparable to previous studies of selected populations.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
In this study, we found that the expression levels of PRR11 and SKA2 were upregulated and have a negative prognotic value in breast cancer. Loss-of-function experiments showed that RNAi-mediated knockdown of PRR11 and/or SKA2 inhibited proliferation, migration, and invasion of breast cancer cells. Mechanistic experiments revealed that knockdown of PRR11 and/or SKA2 caused dysregulation of several downstream genes, including CDK6, TPM3, and USP12, etc. Luciferase reporter assays demonstrated that wild type p53 significantly repressed the PRR11-SKA2 bidirectional promoter activity, but not NF-Y. Interestingly, NF-Y was only ...
Source: BMB Reports - Category: Biochemistry Authors: Tags: BMB Rep Source Type: research
hamed El-Tanani The delivery of anticancer agents to their subcellular sites of action is a significant challenge for effective cancer therapy. Peptides, which are integral to several oncogenic pathways, have significant potential to be utilised as cancer therapeutics due to their selectivity, high potency and lack of normal cell toxicity. Novel Ras protein-Regulator of chromosome condensation 1 (Ran-RCC1) inhibitory peptides designed to interact with Ran, a novel therapeutic target in breast cancer, were delivered by entrapment into polyethylene glycol-poly (lactic-co-glycolic acid) PEG-PLGA polymeric nanoparticles (N...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
U.S. and Guatemalan healthcare institutions are collaborating to bring radiation...Read more on AuntMinnie.comRelated Reading: Cancer rates rising in lower-income countries Breast cancer on rise in low-income countries Breast cancer risk profiles differ in developing nations Air pollution tied to lung cancer, heart disease WHITIA scores win with Guatemala digital x-ray install
Source: Headlines - Category: Radiology Source Type: news
There some evidence in PubMed than medicinal mushrooms may play a role in treatment of some cancers. Most of the claims of medical benefits are bot backed up by high quality studies as of 2019. References are below.---What is turkey tail?Turkey tail is a type of mushroom that grows on dead logs worldwide. It's named turkey tail because its rings of brown and tan look like the tail feathers of a turkey. Its scientific name is Trametes versicolor or Coriolus versicolor. In traditional Chinese medicine, it is known as Yun Zhi. In Japan, it is known as kawaratake (roof tile fungus). Turkey tail has been used in traditional Chi...
Source: Clinical Cases and Images - Blog - Category: Universities & Medical Training Tags: Medicinal Mushrooms Oncology Source Type: blogs
The objective of this review was to summarize the literature describing the development and use of phenotypes for cohort identification of cancer patients. A survey of the literature indexed in PubMed was performed to identify studies using EHR-based phenotypes for use in cancer studies. Specific search criteria were formulated by leveraging a phenotype identification guideline developed by the Phenotypes, Data Standards, and Data Quality Core of the NIH Health Care Systems Research Collaboratory. The final set of articles was examined further to identify 1) the cancer of interest and 2) the different approaches used for p...
Source: Studies in Health Technology and Informatics - Category: Information Technology Tags: Stud Health Technol Inform Source Type: research
Triple-negative breast cancer (TNBC) patients have an increased risk of developing visceral metastases and other primary nonbreast cancers, particularly lung cancer. The differential diagnosis of TNBC metastases and primary cancers from other organs can be difficult due to lack of a TNBC standard immunoprofile. We analyzed the diagnostic value of estrogen receptor, progesterone receptor, human epidermal growth factor receptor, thyroid transcription factor-1 (TTF1), Napsin A, mammaglobin, gross cystic disease fluid protein 15 (GCDFP15), Sry-related HMg-Box gene 10 (SOX10), GATA-binding protein 3 (GATA3), and androgen recept...
Source: The American Journal of Surgical Pathology - Category: Pathology Tags: Original Articles Source Type: research
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