Naevoid acanthosis nigricans or RAVEN (rounded and velvety epidermal naevus) and mosaic FGFR3 and FGFR2 mutations.

Naevoid acanthosis nigricans or RAVEN (rounded and velvety epidermal naevus) and mosaic FGFR3 and FGFR2 mutations.
Br J Dermatol. 2018 Dec 22;:
Authors: Bessis D, Petit A, Battistella M, Bourrat E, Girard C, Pallure V, Marque M, Lacour JP, Vitetta A, Bieth É, Selves J, Solassol J, Vendrell J
Abstract
we read with interest the article by Larsabal et al.1 describing two cases of RAVEN (rounded and velvety epidermal naevus) or naevoid acanthosis nigricans (NAN) associated with mosaic p.Arg252Asn FGFR3 and p.Ser252Trp FGFR2 mutations, adding to a probable case of RAVEN/NAN with comedones linked to the previously reported p.Ser252Trp FGFR2 mutation.2 In the past two years, we had the opportunity to perform molecular analysis for FGFR2 and FGFR3 in seven unrelated patients with RAVEN/NAN and wish to add our experience.
PMID: 30580445 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - December 22, 2018 Category: Dermatology Authors: Bessis D, Petit A, Battistella M, Bourrat E, Girard C, Pallure V, Marque M, Lacour JP, Vitetta A, Bieth É, Selves J, Solassol J, Vendrell J Tags: Br J Dermatol Source Type: research