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ConclusionThis study did not find an increased frequency of tantrums at a preschool age in youth with and without an AS diagnosis. Further research should now consider if autistic tantrums differ from that of typically developing peers.
Authors: Li Q, Zhang A, Xing C, Yuan Y Abstract Chronic kidney disease (CKD) is recognized as a worldwide health problem. Progression of CKD may lead to many serious complications, which are associated with increased morbidity and mortality. Presently, there is no satisfactory treatment. Thus, targeted therapies are urgently needed. The kidneys are second to the heart in terms of mitochondrial abundance and oxygen consumption. Thus, it is not surprising that mitochondrial homeostasis is absolutely essential for the normal function of the kidney. In fact, a number of reports indicate that mitochondria are involved i...
Authors: Li T, Han J, Jia L, Hu X, Chen L, Wang Y Abstract A change in the metabolic flux of glucose from mitochondrial oxidative phosphorylation (OXPHOS) to aerobic glycolysis is regarded as one hallmark of cancer. However, the mechanisms underlying the metabolic switch between aerobic glycolysis and OXPHOS are unclear. Here we show that the M2 isoform of pyruvate kinase (PKM2), one of the rate-limiting enzymes in glycolysis, interacts with mitofusin 2 (MFN2), a key regulator of mitochondrial fusion, to promote mitochondrial fusion and OXPHOS, and attenuate glycolysis. mTOR increases the PKM2:MFN2 interaction by p...
Date: Thursday, 04 18, 2019; Speaker: Timothy H. Moran, Professor, Johns Hopkins University School of Medicine; Building 45 (Natcher Conference Center); Balcony B
Date: Friday, 04 19, 2019; Speaker: Briana Pobiner, Associate Research Professor, Smithsonian National Museum of Natural History; Building 45 (Natcher Conference Center); Balcony B
Date: Friday, 03 22, 2019; Speaker: Prof. David Odde, University of Minnesota, Department of Biomedical Engineering; Building: Building 5; 127
Date: Tuesday, 03 26, 2019; Speaker: Dr. Manzure Mawla; Dr. David Lewis, University of Pittsburgh, Department of Psychiatry; Building: Building 10 (Clinical Center); Lipsett Auditorium; CME Credit
Date: Monday, 04 08, 2019; Speaker: Rachel Green, Ph.D., Bloomberg Distinguished Professor, Johns Hopkins Univ, School of Medicine, Krieger School of Arts&Sci; Building 40; 1201 -1203
Date: Thursday, 04 11, 2019; Speaker: Humaira Gowher, PhD, Assistant Professor, Purdue University; Building: Building 50; 1328
Authors: Han L, Zhang JJ, Jing HF, Qin L Abstract Acute ST-segment elevation myocardial infarction (STEMI) is one of the most common cardiovascular emergencies. With the improvement of living standards, the incidence and mortality rate of STEMI has shown a significant growth trend. PMID: 30892000 [PubMed - as supplied by publisher]