An efficient and simple imidazole-hydrazone ligand for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions in water under infrared irradiation

Publication date: 1 February 2019Source: Journal of Organometallic Chemistry, Volume 880Author(s): Martín Camacho-Espinoza, José Guillermo Penieres-Carrillo, Hulme Rios-Guerra, Selene Lagunas-Rivera, Fernando Ortega-JiménezAbstractA highly efficient catalytic system based on Pd(OAc)2 and an imidazole-hydrazone ligand has been developed for Suzuki–Miyaura cross-coupling reaction in water under aerobic conditions using IR-irradiation. The system can tolerate a wide range of functionalized arylboronic acids and aryl halides. Furthermore, this protocol is also applicable for hetero-aryl bromides.Graphical abstractEfficient catalytic system [imidazole-hydrazone (L1-L3)/Pd(OAc)2] has been developed for Suzuki–Miyaura reaction in water under IR-irradiation. A wide range of substrates could be coupled with phenylboronic acid to afford the desired products in good to excellent yields at low catalyst loadings and low time of reaction.

Source: Journal of Organometallic Chemistry - December 13, 2018 Category: Chemistry Source Type: research