1.25   Å resolution structure of an RNA 20-mer that binds to the TREX2 complex

The 1.25   Å resolution H32:R crystal structure of a 20   nt ribonucleotide that binds to the TREX-2 complex with high affinity shows a double-stranded RNA duplex arranged along a crystallographic 31 axis in which the antiparallel chains overlap by 18 nucleotides and are related by a crystallographic twofold axis. The duplex shows C – A, U – U and C – C noncanonical base pairings together with canonical Watson – Crick A – U and G – C pairs and a G – U wobble.

Source: Acta Crystallographica Section F - September 23, 2015 Category: Biochemistry Authors: Valkov, E. Stewart, M. Tags: RNA noncanonical base pair research communications Source Type: research