Imidazole-hydrazone efficient and simple ligand for palladium-catalyzed Suzuki-Miyaura cross-coupling reaction in water under IR-irradiation

Publication date: Available online 13 November 2018Source: Journal of Organometallic ChemistryAuthor(s): Martín Camacho-Espinoza, José Guillermo Penieres-Carrillo, Hulme Rios-Guerra, Selene Lagunas-Rivera, Fernando Ortega-JiménezAbstractA highly efficient catalytic system based on Pd(OAc)2 and imidazole-hydrazone (L1-L3) has been developed for Suzuki–Miyaura cross-coupling reaction in water under aerobic conditions using IR irradiation. The system can tolerate a wide range of functionalized arylboronic acids and aryl halides. Furthermore, this protocol is also applicable and available for hetero-aryl bromides.Graphical abstractEfficient catalytic system [imidazole-hydrazone (L1-L3)/Pd(OAc)2] has been developed for Suzuki–Miyaura reaction in water under IR-irradiation. A wide range of substrates could be coupled with phenylboronic acid to afford the desired products in good to excellent yields at low catalyst loadings and low time of reaction.

Source: Journal of Organometallic Chemistry - November 14, 2018 Category: Chemistry Source Type: research