Machine learning can predict stroke treatment outcomes
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Publication date: Available online 20 February 2020Source: Life SciencesAuthor(s): Mahsa Hassanipour, Mohammadreza Zarisfi, Vahid Ehsani, Mohammad AllahtavakoliAbstractLate treatment with tissue plasminogen activator (tPA) leads to reperfusion injury and poor outcome in ischemic stroke. We have recently shown the beneficial effects of local brain hypothermia after late thrombolysis. Herein, we investigated whether transient whole-body hypothermia was neuroprotective and could prevent the side effects of late tPA therapy at 5.5 h after embolic stroke. After induction of stroke, male rats were randomly assigned into four g...
Carotid endarterectomy (CEA) is a proven intervention for stroke risk reduction in symptomatic and asymptomatic patients. High-risk patients are often offered carotid stenting to minimize risk and to optimize outcomes. As a referral center for high-risk patients, we sought to evaluate and to analyze our experience with high-risk CEA patients.
Conditions: Stroke; Stroke Sequelae Intervention: Sponsors: Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Centre Hospitalier Universitaire Dinant Godinne - UCL Namur; CHU Ambroise-Paré - Mons Recruiting
Condition: Acute Ischemic Stroke Intervention: Diagnostic Test: hypoperfusion-hypodensity mismatch Sponsor: University Hospital Muenster Completed
Condition: Stroke Interventions: Device: HD-tCES; Device: Sham HD-tCES; Other: Upper extremity rehabilitation Sponsors: Taipei Medical University; Ministry of Science and Technology, R.O.C (Taiwan); National Cheng Kung University Not yet recruiting
Condition: Stroke Intervention: Other: Transitional Care Stroke Intervention (TCSI) Sponsors: McMaster University; Heart and Stroke Foundation of Canada; Canadian Foundation for Healthcare Improvement; Hamilton Health Sciences Corporation; Central South Regional Stroke Network; Rehabilitative Care Alliance; Max Bell Foundation; Health Quality O ntario; Canadian Frailty Network; CorHealth Ontario; Ontario&n...
Conditions: Ischemic Stroke; Hemorrhagic Stroke Interventions: Device: BCI-FES dorsiflexion therapy; Behavioral: Physiotherapy one hour; Behavioral: Physiotherapy two hours Sponsor: University of California, Irvine Recruiting
This study aims to evaluate the safety and efficacy of performing mechanical thrombectomies in older adults.
The use of CTP along with MRA, CTA, and angiography presents unique pearls and pitfalls in the community hospital setting. We hypothesize that this pictorial review and analysis will reveal trends and issues unique to the community setting that have not been exposed in prior research with implications relevant to practice.
Mechanical thrombectomy has been established as the standard of care for LVO (large-vessel occlusion) acute ischemic stroke following the favorable results of several prominent studies. Current guidelines and a recent meta-analysis endorse both thrombectomy techniques of aspiration and stent retriever as comparably effective treatments. The present study was conducted at a community hospital, which was recently certified as a comprehensive stroke center, to evaluate the efficacy of aspiration vs.