Medical News Today: What to know about endometriosis and infertility

Endometriosis causes tissue similar to the uterine lining to grow elsewhere in the body. People with endometriosis may be more likely to experience infertility. In this article, learn about the link between endometriosis and fertility issues, as well as what treatments are available.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Endometriosis Source Type: news

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Previous studies, which were primarily based on the fluorescent in-situ hybridisation (FISH) technique, revealed conflicting evidence regarding male foetal microchimerism in endometriosis. FISH is a relatively...
Source: Reproductive Biology and Endocrinology - Category: Endocrinology Authors: Tags: Research Source Type: research
Anastasiu Endometriosis represents a severe gynecological pathology, defined by implantation of endometrial glands and stroma outside the uterine cavity. This pathology affects almost 15% of women during reproductive age and has a wide range of consequences. In affected women, infertility has a 30% rate of prevalence and endometriosis implants increase the risk of ovarian cancer. Despite long periods of studies and investigations, the etiology and pathogenesis of this disease still remain not fully understood. Initially, endometriosis was related to retrograde menstruation, but new theories have been launched, sugge...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
CONCLUSION: Several coding and non-coding MSY-linked genes displayed microchimerism as evidenced by the presence of their respective DNA inserts, along with their differential transcript expression, in the endometrium during endometriosis and in cases of infertility. PMID: 30760267 [PubMed - in process]
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Abstract The aim of this study was to evaluate the possible effects of endometriosis on early embryo development, by comparing the morphokinetic development of embryos obtained from women with clinically confirmed endometriosis with the ones obtained from tubal factor infertility cases. A total of 82 cycles/patients including 53 cycles with endometriosis and 29 cycles with tubal factor infertility were evaluated. A total of 439 embryos were scored for embryo morphokinetics. Age, body mass index, fertilization rates were similar within the groups. However, the number of previous ART trials was found to be higher (p
Source: Systems Biology in Reproductive Medicine - Category: Reproduction Medicine Authors: Tags: Syst Biol Reprod Med Source Type: research
Publication date: Available online 6 February 2019Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Ertan SaridoganAbstractGynaecologists are frequently involved in the management of conditions which may result in reduced fertility or treatments they administer can lead to infertility. Sexually transmitted infections and pelvic inflammatory disease are the most common cause of tubal damage, gynaecologists can play an important role in the identification and early treatment. Pelvic surgery for conditions such as leiomyoma, ovarian cysts and endometriosis can lead to pelvic adhesions and iatr...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Being infertile is bad enough, but when the infertility is caused by an infertility specialist, this makes it much worse !Sadly, we continue to see lots of patients, whose fertility has been damaged because of poor quality treatment.Here is an example ( names withheld to protect the guilty !)I have a very low amh of 1.16. I have undergone 3 cycles of IUI from Dr G, a gynecologist, none of which were successful. After that, I underwent laparoscopic  surgery by Dr H, an IVF specialist, for removal of endometriosis cyst. During the procedure , the doctor discovered I had a hydrosalpinx in both my fallopian tubes , so the...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Endometriosis is a common gynecologic condition, affecting approximately 10% of reproductive aged women1-3. It commonly presents with pelvic pain, painful periods, and infertility and can significantly impact one ’s quality of life4-6. Early exploration into the pathophysiology of this condition identified race as a risk factor for endometriosis, with the condition predominantly identified in white women7, 8. It is still unclear if there is biological basis for this conviction, or if it can be explained by methodological and social bias that existed in the literature at that time9-11.
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Viewpoint Source Type: research
Abstract MicroRNAs (miRNAs), a class of small non-coding RNA molecules, have been recognized as key post-transcriptional regulators associated with a multitude of human diseases. Global expression profiling studies have uncovered hundreds of miRNAs that are dysregulated in several diseases, and yielded many candidate biomarkers. This review will focus on miRNAs in endometriosis, a common chronic disease affecting nearly 10% of reproductive-aged women, which can cause pelvic pain, infertility, and a myriad of other symptoms. Endometriosis has delayed time-to-diagnosis when compared to other chronic diseases, as the...
Source: Biology of Reproduction - Category: Reproduction Medicine Authors: Tags: Biol Reprod Source Type: research
Authors: De Leo V, Cagnacci A, Cappelli V, Biasioli A, Leonardi D, Seracchioli R Abstract Dysmenorrhea and chronic pelvic pain occur in a significantly higher percentage in women with endometriosis; this benign condition has an incidence ranging from 5 to 10% in the general population, while 35% to 50% of infertile women are affected. Treatment of the symptoms demands integrated approaches with the use of anti-inflammatory substances or drugs and lifestyle changes, including attention to diet. The use of traditional anti-inflammatory drugs over the long term is not very successful because of the fear of side effect...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research
Abstract Endometriosis is an important gynecological disease, affecting 10% of reproductive age women, and associated with pain, infertility, reduced quality of life and high health economic cost. Except for ultrasound detection of ovarian endometriotic cysts, the gold standard for diagnosis is laparoscopy, leading to diagnostic delays of 5-10 years. Accurate noninvasive biomarkers are needed, especially for symptomatic women with a normal gynecological ultrasound, to triage them towards medical or surgical treatment and to monitor their treatment outcome. Such biomarkers are not available today, largely because t...
Source: Biology of Reproduction - Category: Reproduction Medicine Authors: Tags: Biol Reprod Source Type: research
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