World Menopause Day

18 October 2018   is World Menopause Day and October is World Menopause Month.Cochrane Gynaecology and Fertility Group has published multiple reviews assessing the effectiveness and safety of interventions in menopausal women, including peri and postmenopausal women. To celebrate World Menopause Day we have collated a special selection of reviews investigating various treatments  for menopausal symptoms such as hormone therapy, tibolone, relaxation, exercise, and alternative therapy.Black cohosh (Cimicifuga spp.) for menopausal symptomsDehydroepiandrosterone for women in the peri- or postmenopausal phaseHormone therapy for sexual function in perimenopausal and postmenopausal womenHormone therapy for endometriosis and surgical menopauseLong-term hormone therapy for perimenopausal and postmenopausal womenShort-term and long-term effects of tibolone in postmenopausal womenRelaxation for perimenopausal and postmenopausal symptomsAcupuncture for menopausal hot flushesChinese herbal medicine for menopausal symptomsExercise for vasomotor menopausal symptomsBioidentical hormones for women with vasomotor symptomsOestrogen and progestogen hormone replacement therapy for peri-menopausal and post-menopausal women: weight and body fat distributionHormone therapy in postmenopausal women and risk of endometrial hyperplasiaOral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushesLocal oestrogen for vaginal atrophy in postmenopausal womenTestosterone f...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news

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Abstract OBJECTIVE: To determine whether significant hemoperitoneum could be a precursor of deep pelvic endometriosis METHODS: This was a prospective observational cohort study which was carried out in a dedicated gynecological diagnostic unit over a period of 18 months. We included consecutive pre-menopausal, non-pregnant women who attended with severe acute lower abdominal pain and underwent a pelvic ultrasound examination. Women were triaged for surgical or conservative management depending on the cause of pain and severity of their symptoms. Those who were selected for conservative management were invited for ...
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
Authors: Osuga Y, Torng PL, Jeng CJ Abstract We aimed to examine how leuprorelin has been studied for the treatment of women with endometriosis in Asia. We conducted a literature search of PubMed, the Cochrane Library and ClinicalTrials.gov. This review includes randomised trials of women with endometriosis treated with leuprorelin in Asia. Phase I-IV clinical trials published between January 1 2000 and December 31 2016 and written in English were included. Four studies were identified, showing that leuprorelin significantly improves pain and quality of life. The oestrone and oestradiol levels are decreased by leup...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Publication date: Available online 30 November 2018Source: Journal of Minimally Invasive GynecologyAuthor(s): Eugenio Solima, Ida Pino, Giuseppe Scagnelli, Davide Biasoni, Michele Vignali
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
ieva S, Maneschi F, Martire F, Massarotti C, Mattei A, Muzii L, Ottolina J, Pagliardini L, Perandini A, Perelli F, Pino I, Porpora MG, Remorgida V, Scagnelli G, Seracchioli R, Solima E, Somigliana E, Sorrenti G, Ticino A, Venturella R, Viganò P, Vignali M, Zullo F, Zupi E Abstract The incidence of endometriosis in middle-aged women is not minimal compared to that in the reproductive age group. The treatment of affected women after childbearing age to the natural transition toward menopause has received considerably poor attention. Disease management is problematic for these women due to increased contraindi...
Source: Climacteric - Category: Geriatrics Authors: Tags: Climacteric Source Type: research
Publication date: Available online 30 November 2018Source: Journal of Minimally Invasive GynecologyAuthor(s): E Solima, I Pino, G Scagnelli, D Biasoni, M Vignali
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
We report a case of a rectovaginal mass found during a routine pelvic examination in a 60-year-old asymptomatic menopausal woman with no history of hormone replacement therapy, chronic pelvic pain, infertility, or previous gynecologic surgery.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Images in Gynecologic Surgery Source Type: research
We report a case of a rectal-vaginal mass found during a routine pelvic exam in a 60-years-old asymptomatic menopausal woman, with no history of hormone replacement therapy, chronic pelvic pain, infertility or previous gynecological surgery.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: IMAGES IN Gynecological Surgery Source Type: research
Authors: Ye F, Cao W, Lin J, Du Y, Lan L, Dong Y, Zhu J, Zhou Q, Pan X, Lu Y, Zeng F, Xia B, Wang L Abstract To compare the clinical outcomes of intrauterine insemination (IUI) with or without ovulation induction (OI), IUI cycles from January 2008 to December 2017 in Zhoushan Maternity and Child Healthcare Hospital were included, consisting of 455 natural cycles and 536 OI cycles. The overall clinical pregnancy rate did not differ between the two groups (P> 0.05). Stratified by OI medications such as clomiphene (CC), human menopausal gonadotropin (HMG) and follicle stimulating hormone (FSH), the pregnancy rates ...
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
CONCLUSION: The uterus of postmenopausal woman undergo major morphological changes (mainly atrophic lesions in the endometrium and myometrium), leading to a decline in their morphometric parameters over time from the last menstruation. Localization and number of cells showing the expression of steroid receptors: ER-α, PR, and AR in the uterus of postmenopausal women, depending on the time interval from the last menstruation. PMID: 30426467 [PubMed - as supplied by publisher]
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
Authors: Zheng W, Cao L, Xu Z, Ma Y, Liang X Abstract Endometriosis is caused by the growth or infiltration of endometrial tissues outside of the endometrium and myometrium. Symptoms include pain and infertility. Surgery and hormonal therapy are widely used in Western medicine for the treatment of endometriosis; however, the side effects associated with this practice include disease recurrence and menopause, which can severely influence quality of life. Angiogenesis is the main biological mechanism underlying the development of endometriosis. Numerous natural products and Chinese medicines with potent anti-angiogen...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
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