Auditory tasks for assessment of sensory function and affective prosody in schizophrenia

Schizophrenia patients exhibit impairments in auditory-based social cognition, indicated by deficits in detection of prosody, such as affective prosody and basic pitch perception. However, little is known about the psychometric properties of behavioral tests used to assess these functions. The goal of this paper is to characterize the properties of prosody and pitch perception tasks and to investigate whether they can be shortened. The pitch perception test evaluated is a tone-matching task developed by Javitt and colleagues (J-TMT).
Source: Comprehensive Psychiatry - Category: Psychiatry Authors: Source Type: research

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CONCLUSIONS: This study, in line with previous studies, shows that a diagnosis of T1DM is associated with a decreased risk of schizophrenia. This finding of an inverse association between T1DM and schizophrenia may bring an interesting piece, related to autoimmunity, into the schizophrenia-aetiology puzzle. PMID: 31816222 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
ConclusionHere, we examined the psychometric properties of a comprehensive social cognition battery based on the SCOPE study in an Asian schizophrenia population. Continued evaluation and standardization of social cognitive measures are needed to refine our understanding of this construct in schizophrenia.
Source: Schizophrenia Research: Cognition - Category: Psychiatry Source Type: research
AbstractCannabidiol (CBD), a non-psychotropic cannabinoid, demonstrates antipsychotic-like and procognitive activities in humans and in animal models of schizophrenia. The mechanisms of these beneficial effects of CBD are unknown. Here, we examined behavioral effects of CBD in a pharmacological model of schizophrenia-like cognitive deficits induced by repeated ketamine (KET) administration. In parallel, we assessed transcriptional changes behind CBD activities in the prefrontal cortex (PFC), the main brain area linked to schizophrenia-like pathologies. Male Sprague-Dawley rats were injected for 10 days with KET followed by...
Source: Molecular Neurobiology - Category: Neurology Source Type: research
Individuals over age 60 with schizophrenia who were prescribed long-acting injectable (LAI) antipsychotics after being discharged from a hospital were significantly less likely to be rehospitalized within a year than those receiving oral antipsychotics, according to areport inThe American Journal of Geriatric Psychiatry. Also, patients who did need to be admitted again had a longer time to rehospitalization.LAI antipsychotics have been shown to improve adherence to medication in younger populations, which in turn improves overall outcomes. Yet evidence in older populations is lacking.Risk factors for nonadherence in elderl...
Source: Psychiatr News - Category: Psychiatry Tags: adherence to medication elderly with schizophrenia long-acting injectable antipsychotic medications rehospitalization The American Journal of Geriatric Psychiatry Source Type: research
ConclusionsSchizophrenia is featured by disrupted ‘limbic areas-to-thalamus’ rsEC, in contrast with diffusively altered rsFC. Moreover, both rsEC and rsFC contain valuable and complementary information which may be used as diagnostic markers for schizophrenia.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 10 December 2019Source: Journal of Psychiatric ResearchAuthor(s): Monalisa Jena, Rajeev Ranjan, Biswa Ranjan Mishra, Archana Mishra, Santanu Nath, Pallabi Sahu, Bikash Ranjan Meher, Anand Srinivasan, Rituparna Maiti
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Conditions:   Schizophrenia;   Schizo Affective Disorder;   Bipolar Disorder;   Depression Intervention:   Other: Wellth - Financial Incentives Sponsor:   Northwell Health Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: Olanzapine remains a useful antipsychotic albeit with careful monitoring. Further research is needed to compare the different options available to mitigate olanzapine-induced weight gain and to evaluate potential synergism between pharmacological and non-pharmacological treatments. PMID: 31813311 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Psychiatric Services, Ahead of Print.
Source: Psychiatric Services - Category: Psychiatry Authors: Source Type: research
Psychiatric Services, Ahead of Print.
Source: Psychiatric Services - Category: Psychiatry Authors: Source Type: research
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