Efficient and selective aldehyde cyanosilylation catalyzed by Mg-Li bimetallic complex

Publication date: Available online 24 August 2018Source: Journal of Organometallic ChemistryAuthor(s): Jia Li, Ting Yu, Man Luo, Qian Xiao, Weiwei Yao, Li Xu, Mengtao MaAbstractA NCN-pincer ligand-based Mg-Li bimetallic complex [NCN-MgBr2][Li(THF)4] 1 has been employed as an efficient catalyst for cyanosilylation of a wide range of aldehydes with trimethylsilyl cyanide (TMSCN) at room temperature in CDCl3. In addition, catalyst 1 shows a good tolerance towards various functional groups such as amide, acid, ester, heterocyclic and alkene etc. The chemoselective cyanosilylation of aldehydes over ketones was also achieved under these conditions.Graphical abstract

Source: Journal of Organometallic Chemistry - August 25, 2018 Category: Chemistry Source Type: research