Lack of Exercise Can Boost Cancer Risk

Title: Lack of Exercise Can Boost Cancer RiskCategory: Health NewsCreated: 8/13/2018 12:00:00 AMLast Editorial Review: 8/14/2018 12:00:00 AM
Source: MedicineNet Cancer General - Category: Cancer & Oncology Source Type: news

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Publication date: Available online 19 April 2019Source: The American Journal of SurgeryAuthor(s): Tammy Ju, Lisbi Rivas, Kyle Kurland, Sheena Chen, Andrew Sparks, Paul P. Lin, Khashayar VaziriAbstractBackgroundTo identify trends in total and subtotal gastrectomy for middle and distal third gastric adenocarcinoma in the U.S.MethodsNCDB was queried for patients with stage 0-III middle or distal gastric adenocarcinoma treated with total or subtotal gastrectomy. Statistical analysis including cox proportional hazards model was performed to examine overall survival by stage.Results1,628(85%) underwent subtotal gastrectomy and 2...
Source: The American Journal of Surgery - Category: Surgery Source Type: research
CANCER symptoms vary depending on which part of the body is affected by a tumour. You may be at risk of a deadly tumour if you have this painful sign in your chest. Should you see a doctor?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 19 April 2019Source: Seminars in Cancer BiologyAuthor(s): Lingzhi Li, Zhuoyu Bi, Priya Wadgaonkar, Yongju Lu, Qian Zhang, Yao Fu, Chitra Thakur, Li Wang, Fei ChenAbstractAt present, the belief that genetic mutations control every aspect of tumorigenesis is still very popular. Even for the highly debated “bad luck” theory of cancers, it ascertained that random mutation of genes during the self-renewal of somatic stem cells is responsible for cancer initiation. Logically, most of the new therapeutic strategies so far, from molecular targeting to precision medicine or personalize...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 16 April 2019Source: Seminars in Cancer BiologyAuthor(s): Samanta Salvi, Massimiliano Bonafè, Sara BravacciniAbstractThe possibility that a receptor for androgen is expressed in Breast Cancer (BC) is fascinating given that the tumor is predominantly estrogen-dependent.The androgen receptor (AR) is emerging as a new marker and a potential new therapeutic target in the treatment of BC patients. The recent availability of selective AR inhibitors (e.g. bicalutamide, enzalutamide, apalutamide) approved for the treatment of prostate cancer has opened up the possibility to use them in BC ...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
ConclusionsThe study highlights increasing incidence of colon cancer in younger subjects and a decrease in incidence rates for rectal cancer in females.
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
ConclusionThese data suggest that combinational treatment with NK cell–based immunotherapy and cetuximab may be promising for patients with TKI-resistant NSCLC.
Source: Cytotherapy - Category: Cytology Source Type: research
Conclusion: The data suggests that peripheral blood expression profiles could be used to monitor tobacco-induced HNSCC as well as the treatment response. PMID: 31002268 [PubMed - as supplied by publisher]
Source: Biomarkers - Category: Research Tags: Biomarkers Source Type: research
Authors: Zhang H, Song Y, Yang C, Wu X Abstract Colorectal cancer (CRC) is a highly heterogeneous disease worldwide. Long non‑coding RNA (lncRNA) tumor suppressor candidate 7 (TUSC7) plays a crucial role in the development of several cancers. However, the role of TUSC7 in the tumorigenesis of CRC has not been explored. The TUSC7‑overexpressing CRC cell lines SW480 and CaCo‑2 were generated to investigate the effects of TUSC7 on the growth, migration, invasion and epithelial‑mesenchymal transition (EMT) of CRC cells. CCK‑8, wound‑healing and Transwell assays were used to evaluate CRC cell proliferation, ...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Cheng Z, Wei W, Wu Z, Wang J, Ding X, Sheng Y, Han Y, Wu Q Abstract Actin-related protein 2/3 complex (ARPC2) is an actin‑binding component involved in the regulation of actin polymerization. It mediates the formation of branched actin networks and contacts the mother actin filament. Migration and invasion are key processes which enable tumor cells to infiltrate blood vessels or lymphatic vessels, and the actin pathway plays a very important role. Given that ARPC2 is critical to this progression, the present study focused on ARPC2 activity in breast cancer (BrCa) cell invasion and migration. Limited data...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
Authors: Xi HQ, Cui JX, Shen WS, Wu XS, Bian SB, Li JY, Song Z, Wei B, Chen L Abstract An interested reader drew to the attention of the Journal that the western blot featured in Fig. 3B of the above paper also appeared as Fig. 3D in the following publication, featuring many of the same authors: Xi HQ, Cai AZ, Wu XS et al: Leucine‑rich repeat‑containing G‑protein‑coupled receptor 5 is associated with invasion, metastasis, and could be a potential therapeutic target in human gastric cancer. Br J Cancer 110: 2011‑2020, 2014. After having consulted the authors about this ma...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
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