Meet the high-powered Washington lobbyist with Down syndrome

Kayla McKeon is focused on passing a law that would make it illegal to pay people with disabilities anything less than minimum wage
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news

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American Journal on Intellectual and Developmental Disabilities,Volume 124, Issue 4, Page 293-308, July 2019.
Source: American Journal on Intellectual and Developmental Disabilities - Category: Disability Authors: Source Type: research
American Journal on Intellectual and Developmental Disabilities,Volume 124, Issue 4, Page 324-338, July 2019.
Source: American Journal on Intellectual and Developmental Disabilities - Category: Disability Authors: Source Type: research
American Journal on Intellectual and Developmental Disabilities,Volume 124, Issue 4, Page 354-373, July 2019.
Source: American Journal on Intellectual and Developmental Disabilities - Category: Disability Authors: Source Type: research
(Natural News) The latest perverse fetish of the lesbian, gay, bisexual, transgender, queer, and pedophile (LGBTQP) cult is to prey on young children with mental disabilities, including little ones with Down syndrome or autism, and exploit them as transgender drag queens for sexual entertainment. During a recent episode of “The Alex Jones Show,” InfoWars host...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Changes in Body Composition and Physical Fitness in Adolescents with Down Syndrome: The UP&DOWN Longitudinal Study. Child Obes. 2019 Jun 06;: Authors: Suarez-Villadat B, Veiga OL, Villagra A, Izquierdo-Gomez R, UP&DOWN Study Group Abstract Background: Adolescents with Down syndrome (DS) demonstrate higher values of body composition and lower levels of physical fitness when compared with their peers with typically developing (TD) or their peers with intellectual disability but without DS. Objective: To examine, during a 2-year period, changes in indicators of body composition and physical fitness co...
Source: Childhood Obesity - Category: Eating Disorders & Weight Management Tags: Child Obes Source Type: research
Abstract Studies in mice suggest that Olig2 gene dosage alters cerebral cortical interneuron development and contributes to trisomy-21/Down-syndrome-related intellectual disability. Xu et al. (2019) extend these studies through the remarkable use of cerebral organoid and human iPSC/mouse brain chimera experimental systems that provide an opportunity for the development of novel therapeutics. PMID: 31173710 [PubMed - in process]
Source: Cell Stem Cell - Category: Stem Cells Authors: Tags: Cell Stem Cell Source Type: research
Publication date: Available online 28 May 2019Source: NeuroImage: ClinicalAuthor(s): Jacob Levman, Allissa MacDonald, Nicole Baumer, Patrick MacDonald, Natalie Stewart, Ashley Lim, Liam Cogger, Tadashi Shiohama, Emi TakahashiAbstractDown syndrome (DS) is a genetic disorder caused by an extra copy of all or part of chromosome 21 and is characterized by intellectual disability. We performed a retrospective analysis of 47 magnetic resonance imaging (MRI) examinations of participants with DS (aged 5 to 22 years) and compared them with a large cohort of 854 brain MRIs obtained from neurotypical participants (aged 5 to 32 ye...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Fragile X syndrome(FXS) is most common congenital hereditary disease of low intelligence after Down Syndrome. Its main pathogenic gene is Fragile X mental retardation 1 (FMR1) gene associated with intellectual disability, autism and Fragile X-related primary ovarian insufficiency (FXPOI) and Fragile X-associated tremor/ataxia syndrome (FXTAS). Fmr1 gene transcription leads to the absence of fragile X mental retardation protein (FMRP). How to relieve or cure disorders associated with FXS has also become a clinically disturbing problem. Previous studies have recently shown that Long noncoding RNAs (lncRNA) contribute to the ...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conclusion: The high rate of chromosomal abnormalities found in the Moroccan patients studied demonstrates the capital importance of cytogenetic evaluation in patients who show ID or any clinical development abnormality.Hum Hered 2017/2018;83:274 –282
Source: Human Heredity - Category: Genetics & Stem Cells Source Type: research
In conclusion, we further advanced the molecular understanding of mitochondrial dysfunction in RTT. Intensified mitochondrial O2 consumption, increased mitochondrial ROS generation and disturbed redox balance in mitochondria and cytosol may represent a causal chain, which provokes dysregulated proteins, oxidative tissue damage, and contributes to neuronal network dysfunction in RTT. Introduction Rett syndrome (RTT) is a progressive neurodevelopmental disorder. It primarily affects females, who show the first obvious symptoms within 6–18 months after birth. Among the characteristics are a regression of mental ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
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