The effect of Adalimumab on the vasculature in psoriatic skin lesions.

DISCUSSION: Adalimumab treatment of psoriasis causes an evident reduction in endothelial cell proliferation, vascular network size and vessel diameter, parallel to the clinical improvement. Vascular parameters do not capture early improvement to adalimumab treatment. However, (non-) invasive measurement of vascular function parallels the clinical improvement and may be a valuable marker for disease activity. PMID: 30074865 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research