Factors associated with development of re-nonunion after primary revision in femoral shaft nonunion subsequent to failed intramedullary nailing

Currently, there remains a lack of consensus regarding factors predictive of complication such as re-nonunion after primary revision in femoral shaft nonunion subsequent to failed intramedullary nailing (IMN)....
Source: Journal of Orthopaedic Surgery and Research - Category: Orthopaedics Authors: Tags: Research article Source Type: research

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Publication date: Available online 20 September 2019Source: Biocybernetics and Biomedical EngineeringAuthor(s): Tasleem Kausar, MingJiang Wang, Muhammad Idrees, Yun LuAbstractAmong the predominant cancers, breast cancer is one of the main causes of cancer deaths impacting women worldwide. However, breast cancer classification is challenging due to numerous morphological and textural variations that appeared in intra-class images. Also, the direct processing of high resolution histological images is uneconomical in terms of GPU memory. In the present study, we have proposed a new approach for breast histopathological image ...
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Publication date: Available online 20 September 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Gerwyn Morris, Basant K. Puri, Adam J. Walker, Michael Maes, Andre F. Carvalho, Ken Walder, Michael BerkAbstractActivated immune-inflammatory, oxidative and nitrosative stress (IO&NS) pathways and consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric disorders including major depression, bipolar disorder and schizophrenia. They offer independent and shared contributions to pathways underpinning medical comorbidities including insulin resistance, metabolic syndrome, obesity and card...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Publication date: Available online 20 September 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Hilary K. Lambert, Katie A. McLaughlinAbstractSmaller hippocampal volume is associated with increased risk for PTSD following trauma, but the hippocampal functions involved remain unknown. We propose a conceptual model that identifies broad impairment in hippocampus-dependent associative learning as a vulnerability factor for PTSD. Associative learning of foreground cues and background context is required to form an integrated representation of an event. People with poor associative learning may have difficulty rem...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
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Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Publication date: Available online 20 September 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Fu YuAbstractEarly postnatal experience has a profound influence on the development of organisms. In this integration, we provide a novel framework of the neurobehavioral pathways through which positive early postnatal experience acts to enhance adult reward sensitivity. The heterogeneity of the construct of reward and the underlying neurotransmitter systems (i.e., dopamine in incentive reward, opioids in consummatory reward, and oxytocin in orienting the reward systems to social cues) are first described as a mean...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Publication date: December 2019Source: NeuroImage, Volume 203Author(s): Javier Bernacer, Ivan Martinez-Valbuena, Martin Martinez, Nuria Pujol, Elkin O. Luis, David Ramirez-Castillo, Maria A. PastorAbstractWhen humans make decisions, objective rewards are mainly discounted by delay, risk and effort. Whereas recent research has demonstrated that several brain areas process costs and code subjective value in effort-based decision making, it remains obscure how neural activity patterns change when effort costs are reduced due to the acquisition of healthy habits, such as moving from sedentary to active lifestyles. Here, a samp...
Source: NeuroImage - Category: Neuroscience Source Type: research
In this study, we aim at characterizing age-related effects of 16p11.2 copy number variants by analyzing a group with a broad age range including younger individuals. A large normative developmental dataset was used to accurately adjust for effects of age. We normalized volumes of segmented brain regions as well as volumes of each voxel defined by tensor-based morphometry. Results show that the total intracranial volumes, the global gray and white matter volumes are respectively higher and lower in deletion and duplication carriers compared to control subjects at 4.5 years of age. These differences remain stable through ch...
Source: NeuroImage - Category: Neuroscience Source Type: research
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Source: NeuroImage - Category: Neuroscience Source Type: research
Publication date: December 2019Source: NeuroImage, Volume 203Author(s): Thomas Hartmann, Nathan WeiszAbstractThe efferent auditory system suggests that brainstem auditory regions could also be sensitive to top-down processes. In electrophysiology, the Frequency Following Response (FFR) to speech stimuli has been used extensively to study brainstem areas. Despite seemingly straight-forward in addressing the issue of attentional modulations of brainstem regions by means of the FFR, the existing results are inconsistent. Moreover, the notion that the FFR exclusively represents subcortical generators has been challenged. We ai...
Source: NeuroImage - Category: Neuroscience Source Type: research
Publication date: December 2019Source: NeuroImage, Volume 203Author(s): Naama Mayseless, Grace Hawthorne, Allan L. ReissAbstractIt is often assumed that groups of individuals can work together to achieve innovation and solve complex problems they are unable to solve on their own. One of the underlying assumptions is that a group can be more creative and innovative than single individuals. Previous research has begun to examine the process by which problem solving occurs in teams looking to achieve innovation. Despite this progress, a clear, brain-based model that informs how team interactivity contributes and impacts the o...
Source: NeuroImage - Category: Neuroscience Source Type: research
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