Copper-catalyzed cross-coupling reactions of 5-stibano-1,2,3-triazoles with bromoalkynes under aerobic conditions: Synthesis of 5-alkynyl-1,2,3-triazoles

Publication date: Available online 9 July 2018Source: Journal of Organometallic ChemistryAuthor(s): Mizuki Yamada, Daiki Matsuura, Mai Hasegawa, Yuki Murata, Naoki Kakusawa, Mio Matsumura, Shuji YasuikeAbstractCu-catalyzed cross-coupling of 5-stibano-1,2,3-triazoles with bromoalkynes is described. The reaction of 5-stibanotriazoles with bromoalkynes under aerobic conditions in DMF, using a combination of 10 mol% of Cu2O and 1,10-phenanthroline, produced a variety of 5-alkynyltriazoles in moderate-to-excellent yields. This reaction is the first example of Cu-catalyzed C(Ar)–C(sp) bond formation using trivalent organoantimony compounds.Graphical abstract

Source: Journal of Organometallic Chemistry - July 9, 2018 Category: Chemistry Source Type: research