Is It Time to Stop Using Warfarin for DVT?

Does rivaroxaban for treatment of deep venous thrombosis (DVT) warrant changing our current treatment with vitamin K antagonists (VKAs)? Dr. Orman examines the evidence.
Source: Emergency Medicine News: SoundsBites: Q&A - Category: Emergency Medicine Source Type: podcasts

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Authors: Kimura N, Tsuchiya A, Oda C, Kimura A, Hosaka K, Tominaga K, Hayashi K, Abé T, Umezu H, Terai S Abstract A 75-year-old woman with liver cirrhosis was admitted for treatment of portal vein thrombosis (PVT). Computed tomography (CT) showed PVT, massive ascites, and multiple abdominal organ embolism. Blood tests revealed a decreased liver function (Child-Pugh grade C). Language impairment followed by progressive left hemi-paralysis was subsequently detected. Magnetic resonance imaging revealed multiple small acute cerebral infarctions and, on CT, a 30-mm bladder tumour; a biopsy specimen examination sh...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Publication date: Available online 27 May 2020Source: Respiratory Medicine Case ReportsAuthor(s): Kosuke Tsuruno, Kazunori Tobino, Mitsukuni Sakabe, Masanobu Okahisa, Saori Nishizawa, Kohei Yoshimine, Yuki Ko, Hiromi Ide
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Authors: Tomiyama H, Shiina K Abstract The brachial-ankle pulse wave velocity (brachial-ankle PWV), which is measured simply by wrapping pressure cuffs around the four extremities, is a simple marker to assess the stiffness of the medium- to large- sized arteries. The accuracy and reproducibility of its measurement have been confirmed to be acceptable. Risk factors for cardiovascular disease, especially advanced age and high blood pressure, are reported to be associated with an increase of the arterial stiffness. Furthermore, arterial stiffness might be involved in a vicious cycle with the development/progression o...
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
CONCLUSION: The results of our study suggest that the enhancement of β-VLDL catabolism is the major mechanism for atheroprotective effects of EL in Tg rabbits. PMID: 32448826 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research
Coronavirus Disease 2019 (COVID-19) is a major health issue around the world with many clinical facets including vascular ones. In this regard, the interesting case reported by Giacomelli and collaborators invites to discuss some aspects of acute arterial thrombosis in course of COVID-19 pneumonia.1 Blood hypercoagulability, a typical feature of this viral infection, can cause both venous and arterial thromboses, as recently described, more commonly involving medium-sized arteries (supra-aortic trunks, cerebral arteries).
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Correspondence Source Type: research
We describe an early placement of inferior vena cava filter added to the therapeutic anticoagulation to prevent a massive pulmonary embolism.
Source: Annals of Vascular Surgery - Category: Surgery Authors: Tags: Case Report Source Type: research
ConclusionsGPs and patients are waiting for the other to mention issues surrounding AF treatment such as switching, use of thrombosis service, and number of pills to take first. The perceptions and experiences of patients with AF regarding their disease and treatment highly influence the decisions GPs make, together with these patients, as well as considerations that patients have regarding their treatment; GPs need to be aware of their AF patients ’ perceptions and experiences with their condition and medication’ in order to facilitate discussions with patients and improve clinical outcomes.
Source: Cardiology and Therapy - Category: Cardiology Source Type: research
This study retrospectively analyzed the data of patients with atrial fibrillation who received anticoagulant therapy from July 2015 to December 2018 at two centers —the Fujian Medical University Union Hospital and Fuzhou Second Hospital Affiliated to Xiamen University. Demographic data, clinical findings, and laboratory results were collected from the hospital records. Patients were followed up for 6 months. The performance of four bleeding risk scores (New Score, RIETE Score, Cuschieri et al. Score, de Groot et al. Score) for prediction of gastrointestinal bleeding was assessed using the area under the curve. A...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
AbstractThe role of inflammation in thrombotic complications of primary antiphospholipid syndrome (PAPS) is controversial. The aim of this study was to evaluate levels of inflammation and coagulation markers in patients with thrombotic PAPS (t-PAPS). Patients with t-PAPS and individuals with no history of thrombosis were enrolled. The association of t-PAPS with levels of tumor necrosis factor (TNF)- α, C-reactive protein (hs-CRP), interferon (IFN)-α, interleukins (IL)-6, -8, factor VIII (FVIII), von Willebrand factor (VWF) and tissue factor (TF) was evaluated by regression models. The levels of these markers we...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Infection by the 2019 novel coronavirus (COVID-19) has been reportedly associated with a high risk of thrombotic complications. So far information is scarce and rapidly emerging.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Full Length Article Source Type: research
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