Chylothorax as Rare Manifestation of Pleural Involvement in Waldenstr öm Macroglobulinemia: Mechanisms and Management.

Chylothorax as Rare Manifestation of Pleural Involvement in Waldenström Macroglobulinemia: Mechanisms and Management. Lymphology. 2016 Dec;49(4):210-17 Authors: Leoncini G, Campisi CC, Fraternali Orcioni G, Patrone F, Ferrando F, Campisi C Abstract Here we report the clinical, pathological, and immunological features of a rare case of Waldenström macroglobulinemia (WM) with pleural infiltrations. An atypical chylothorax, successfully treated by videothoracoscopy, represented the main clinical feature of this case of low-grade lymphoplasmacytic lymphoma. Pleuropulmonary manifestations are rare (from 0 to 5% of cases) in WM, with chylothorax observed in just seven patients worldwide. In addition to describing this uncommon clinical presentation, we investigate hypothetical pathogenetic mechanisms causing chylothorax and through an up-todate review of available literature furnish helpful suggestions for diagnosis and management of chylothorax in WM patients. PMID: 29908554 [PubMed - in process]
Source: Lymphology - Category: Internal Medicine Tags: Lymphology Source Type: research