Scientists find existing asthma drug can reverse memory loss in mice

Temple University experts claimed their findings on the drug zileuton open up a potential new route to stop the aggressive progression of Alzheimer's disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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CONCLUSIONS: The Expert Group foresee an important role for EGb 761® , used alone or as an add-on therapy, in the treatment of MCI and dementias, particularly when patients do not derive benefit from acetylcholinesterase inhibitors or NMDA antagonists. EGb 761® should be used in alignment with local clinical practice guidelines. PMID: 30648358 [PubMed - in process]
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Tags: CNS Neurosci Ther Source Type: research
More people are having asthma attacks than five years ago, data  suggests. Charity Asthma UK said. Kelly May, 31, from London, has had hundreds of 'terrifying' attacks since she was a baby.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Kowalski K, Mulak A Abstract Disturbances along the brain-gut-microbiota axis may significantly contribute to the pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent cause of dementia characterized by a progressive decline in cognitive function associated with the formation of amyloid beta (Aβ) plaques and neurofibrillary tangles. Alterations in the gut microbiota composition induce increased permeability of the gut barrier and immune activation leading to systemic inflammation, which in turn may impair the blood-brain barrier and promote neuroinflammation, neura...
Source: Journal of Neurogastroenterology and Motility - Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research
(MedPage Today) -- Frail older adults with Alzheimer's pathology showed more symptoms
Source: MedPage Today Psychiatry - Category: Psychiatry Source Type: news
Every three seconds in the UK, someone has an asthma attack which could be life-threatening, a charity says.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
ConclusionThis study shows a link between work-related stress and incident asthma which seems to be confined to women. This study adds evidence about the association of work-related stress and asthma in young adults and can contribute to prevention for that particular age group.
Source: International Archives of Occupational and Environmental Health - Category: Occupational Health Source Type: research
Qiyang Shou, Lu Jin, Jiali Lang, Qiyuan Shan, Zhunan Ni, Changpei Cheng, Qinglin Li, Huiying Fu, Gang Cao
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Long Pang, Junjie Wang, Lingling Zhao, Chunyu Wang, Hui Zhan
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Much of the signaling that passes between cells travels via varieties of extracellular vesicle, tiny membrane-bound packages that contain a wide variety of presently poorly cataloged molecules. The varieties of vesicle are also poorly catalogued, and are at present given a loose taxonomy based on size. No doubt there are many subtypes within any given size category, depending on circumstance and mechanism, with the contents varying characteristically by subtype. Nothing is simple in cellular biology. Vesicles are currently a subject of growing interest in many fields of medical research. In regenerative medicine, fo...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
Many of today’s most popular drugs can make you forgetful. They inhibit your brain’s chemical messengers. And this blocks your concentration, memory and ability to focus. More specifically, these drugs block the activity of a neurotransmitter in your brain called acetylcholine. Acetylcholine is directly involved in learning and memory. And blocking it is a risky business… I’ve seen confusion, memory loss, and declining mental skills in patients who take these drugs. New research confirms what I see in my own practice. One recent study found that people taking these kinds of drugs had shrunken ar...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
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