Scientists find existing asthma drug can reverse memory loss in mice

Temple University experts claimed their findings on the drug zileuton open up a potential new route to stop the aggressive progression of Alzheimer's disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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ConclusionThese findings suggest that LTP-like cortical plasticity may represent a neurophysiological surrogate of memory in AD patients by evaluating the weight of pathological changes responsible for cognitive dysfunction.
Source: Brain Stimulation - Category: Neurology Source Type: research
In this report, we propose that the molecular mechanisms of beneficial actions of CR should be classified and discussed according to whether they operate under rich or insufficient energy resource conditions. Future studies of the molecular mechanisms of the beneficial actions of CR should also consider the extent to which the signals/factors involved contribute to the anti-oxidative, anti-inflammatory, anti-tumor and other CR actions in each tissue or organ, and thereby lead to anti-aging and prolongevity. RNA Interference of ATP Synthase Subunits Slows Aging in Nematodes https://www.fightaging.org/archives/...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
(Natural News) Cranberry juice, which is full of antioxidants, demonstrates various health benefits and it is often used to prevent age-related brain decline. According to a study, cranberry extract (CBE) may even help treat Alzheimer’s disease. A natural part of life, aging is often linked to the accumulation of damages “at the molecular, cellular, and organ levels.” Damage...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Dear Carol: My parents are so isolated in their home because their neighborhood is so changed that they want to move to assisted living. Apparently, they’ve heard good things about these facilities from friends but most of these friends are better off financially than my parents. I’ve tried to convince them to come north to be near me, but that’s not going to happen, and I have a job that I’m firmly planted in up north so I can’t move there. I’ll fly down to help them decide about a facility, and again to move, but I’d like assistance in sorting the choices. Can I trust the se...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
DiscussionOur study demonstrated the robustness of a multisite Centiloid [11C]PIB-PET study and established a range of pathology-based CL thresholds.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
ConclusionMost potent three chemicals (ZA-2, 6 and 7) could be considered as bioactive to ensure the robust quality of the enriched fraction of ZAF with defined XO inhibition potential. Therefore, either single purified component or their enriched fraction could be a better choice for the management of gout than the crude extract of ZAF. Developed HPLC method is suitable for quality assurance analysis and process control of ZAF derived product intended for gout management. XO inhibitory potential exhibited by the characterized compounds validate the traditional use of this ZAF for the treatment of gout. Further, a detailed...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
There’s an argument that has been batted around in online conversations, one that I thought that, because it was so patently absurd and so readily disproven, it would simply disappear into the blogosphere . . . but it hasn’t. So let’s talk about this idea. The idea goes like this: Because glyphosate is liberally applied to wheat, including its application as a desiccant and for weed control pre-planting, during maturation, and pre-harvest, the high concentrations of this herbicide in wheat products are the cause for all the problems that emerge with wheat consumption. It means that, minus glyphosate, whea...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates gluten-free glyphosate grain-free grains Inflammation roundup undoctored wheat belly Source Type: blogs
Difference between two exhaled nitric oxide analyzers, NIOX VERO® electrochemical hand-held analyzer and NOA280i® chemiluminescence stationary analyzer. J Asthma. 2018 Oct 18;:1-6 Authors: Tanabe Y, Harada N, Ito J, Matsuno K, Takeshige T, Harada S, Takemasa M, Kotajima M, Ishimori A, Katsura Y, Makino F, Atsuta R, Takahashi K Abstract BACKGROUND: Fractional exhaled nitric oxide (FENO) is useful for the evaluation of eosinophilic airway inflammation, including that seen in asthma. Although a new electrochemical hand-held FENO analyzer, the NIOX VERO® (Aerocrine AB, Solna, Sweden), is clinic...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
CONCLUSIONS: Simple ways to overcome emotional dependency and fortify self-esteem (exercises promoting self-awareness, opportunities cultivating decision-making, and a considerable freedom-of-choice to experience consequences) worth recommending to parents of children with asthma. Patients with suspected mental illness must be referred for psychiatric evaluations. PMID: 30335531 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Many of today’s most popular drugs can make you forgetful. They inhibit your brain’s chemical messengers. And this blocks your concentration, memory and ability to focus. More specifically, these drugs block the activity of a neurotransmitter in your brain called acetylcholine. Acetylcholine is directly involved in learning and memory. And blocking it is a risky business… I’ve seen confusion, memory loss, and declining mental skills in patients who take these drugs. New research confirms what I see in my own practice. One recent study found that people taking these kinds of drugs had shrunken ar...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
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