Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response [Applied Biological Sciences]
Vaccination in the developing world is hampered by limited patient access, which prevents individuals from receiving the multiple injections necessary for protective immunity. Here, we developed an injectable microparticle formulation of the inactivated polio vaccine (IPV) that releases multiple pulses of stable antigen over time. To accomplish this, we established...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Stephany Y. Tzeng, Kevin J. McHugh, Adam M. Behrens, Sviatlana Rose, James L. Sugarman, Shiran Ferber, Robert Langer, Ana Jaklenec Tags: PNAS Plus Source Type: research