Ustekinumab: Novel Help in Vasculitis?

(MedPage Today) -- Steroid-sparing effects demonstrated in small pilot study
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news

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CONCLUSIONS: Small bowel location and longer abdominal pain duration may help distinguish vasculitis-induced bowel perforation from other etiologies. Overall mortality in patients with vasculitis and bowel perforation is increased, highlighting the importance of prompt diagnosis and management. PMID: 30652682 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Authors: Pagnoux C, Nair P, Xi Y, Khalidi NA, Carette S, Cuthbertson D, Grayson PC, Koening CL, Langford CA, McAlear CA, Moreland LW, Monach PA, Seo P, Specks U, Sreih AG, Ytterberg SR, Tyrrell PN, Merkel PA, Vasculitis Clinical Research Consortium Abstract OBJECTIVES: The pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) remains poorly understood, and may overlap with eosinophilic asthma and primary hypereosinophilic syndrome (HES). The aim of this study was to analyse a panel of serum cytokines and chemokines as markers of disease activity in patients with these conditions. METHODS: The lev...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Publication date: Available online 17 January 2019Source: Surgery (Oxford)Author(s): Manj GohelAbstractThe management of patients with chronic leg ulcers represents an enormous burden to healthcare services in the United Kingdom. Most leg ulcers are due to chronic venous hypertension, although arterial compromise, malignancy, vasculitis and other medical disorders are also recognized causes. The assessment of patients with chronic leg ulceration should include a detailed history and clinical examination, supported by relevant investigations. Ankle-brachial pressure index measurement and non-invasive venous (± arteri...
Source: Surgery (Oxford) - Category: Surgery Source Type: research
Publication date: Available online 17 January 2019Source: Joint Bone SpineAuthor(s): Xavier Romand, Chloé Bernardy, Minh Vu Chuong Nguyen, Anaïs Courtier, Candice Trocme, Margot Clapasson, Marie-Hélène Paclet, Bertrand Toussaint, Philippe Gaudin, Athan BailletABSTRACTCalprotectin is a calcium binding protein produced by neutrophils and monocytes locally at the site of inflammation in order to trigger the innate immunity receptors. This unique characteristic makes it a good proxy for evaluation of local inflammation in chronic inflammatory rheumatic diseases. Complete data suggest, in inflammatory ...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
This video covers the pathophysiology of vasculitis in general, as well as more specific conditions like giant cell arteritis, Takayasu arteritis, Kawasaki disease, polyarteritis nodosa, and others.Osmosis
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Rheumatology Commentary Source Type: news
Author Correction: Pathogenesis and therapeutic interventions for ANCA-associated vasculitis, Published online: 17 January 2019; doi:10.1038/s41584-019-0168-zAuthor Correction: Pathogenesis and therapeutic interventions for ANCA-associated vasculitis
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Source Type: research
Kawasaki disease (KD) is an acute febrile childhood systemic vasculitis that disturbs coronary arteries. The pathogenesis remains unknown. The study of phosphorylated proteins helps to elucidate the relevant p...
Source: BMC Cardiovascular Disorders - Category: Cardiology Authors: Tags: Research article Source Type: research
The management of patients with chronic leg ulcers represents an enormous burden to healthcare services in the United Kingdom. Most leg ulcers are due to chronic venous hypertension, although arterial compromise, malignancy, vasculitis and other medical disorders are also recognized causes. The assessment of patients with chronic leg ulceration should include a detailed history and clinical examination, supported by relevant investigations. Ankle-brachial pressure index measurement and non-invasive venous ( ± arterial) imaging using colour duplex are the principal investigations.
Source: Surgery (Medicine Publishing) - Category: Surgery Authors: Tags: Vascular surgery – II Source Type: research
PMID: 30653244 [PubMed - as supplied by publisher]
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
Authors: Villani A, De Fata Salvatores G, Nappa P, Megna M, Fabbrocini G, Napolitano M Abstract PMID: 30636399 [PubMed - as supplied by publisher]
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
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