Hodgkin's Lymphoma of the Breast Hodgkin's Lymphoma of the Breast
This unusual case details the diagnosis and management of Hodgkin's lymphoma which presented in a male patient as gynecomastia and breast tenderness.Applied Radiology
Publication date: Available online 20 October 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): R. Sacco, S. Shah, R. Leeson, V. Moraschini, C.F. de Almeida Barros Mourão, O. Akintola, A. LalliAbstractTumour necrosis factor-α (TNF-α) inhibitors are increasingly being used as immunomodulators to manage inflammatory conditions such as rheumatoid arthritis and Crohn’s disease. Reported serious side effects include an increased incidence of lymphoma and greater susceptibility to infections such as tuberculosis. The aim of this systematic review was to find out whether there is an ...
ConclusionsShort-term exercises do not appear to convey benefits to quality of life and other psychosocial outcomes. Subgroup analysis showed that physical activity together with mental exercise may be more beneficial to lymphoma patients, but it needs more research to verify this finding. The interpretation of this result should be cautious due to the baseline difference, completion efficiency of intervention process, and high heterogeneity.
Leukemia, Published online: 21 October 2019; doi:10.1038/s41375-019-0609-3Rituximab in newly diagnosed stage IA nodular lymphocyte-predominant Hodgkin lymphoma: long-term follow-up of a phase 2 study from the German Hodgkin Study Group
Leukemia, Published online: 21 October 2019; doi:10.1038/s41375-019-0611-9Targeting BCL-W and BCL-XL as a therapeutic strategy for Hodgkin lymphoma
Authors: Navarro-Almenzar B, Cabañas Perianes V PMID: 31627961 [PubMed - as supplied by publisher]
Authors: Martínez-Esteve A, Moreno-Caballero M, Jiménez-Granero P, Cobo-Rodríguez A, Infante-de-la-Torre JR, Serrano-Vicente J, Rayo-Madrid JI, Martín-Marcuartu JJ PMID: 31623822 [PubMed - as supplied by publisher]
This report highlights that a focal 18F-FDG uptake in the testicular region with unexplained gynecomastia should suggest the diagnosis of an estrogen-secreting Leydig cell tumor on 18F-FDG PET/CT.
Abstract: Interpretation of 18F-FDG PET/CT studies in breast is challenging owing to nonspecific FDG uptake in various benign and malignant conditions. Benign conditions include breast changes in pregnancy and lactation, gynecomastia, mastitis, fat necrosis, fibroadenoma, intraductal papilloma, and atypical ductal hyperplasia. Among malignancies, invasive ductal carcinoma and invasive lobular carcinoma are common histological types of breast carcinoma. Rarely, other unusual histological types of breast carcinomas (eg, intraductal papillary carcinoma, invasive micropapillary carcinoma, medullary carcinoma, mucinous carcinom...
Abstract Primary breast lymphoma is a rare type of non-Hodgkin lymphoma and usually affects women, although a few cases have been reported in men. Chemotherapy and radiation therapy, or a combination of both, are frequently administered for treatment of primary breast lymphoma, as local control by surgical resection is poor. No standard therapy has been established, and the optimal radiation dose and irradiation field for male patients are unknown. The present report describes a 75-year-old man with bilateral cirrhosis-induced gynecomastia who was diagnosed with primary breast lymphoma; specifically, diffuse large...