Successful Use of Bortezomib –Lenalidomide Combination as Treatment for a Patient With Plasmablastic Lymphoma

Plasmablastic lymphoma (PBL) is a rare type of non-Hodgkin lymphoma (NHL) with a predilection for the oral cavity. It is more commonly found in elderly patients infected with HIV and Epstein-Barr virus (EBV). Since PBL was first described in 1997,1 most cases have been described in HIV-positive patients.2 Some instances have been described in HIV-negative patients involving other organs; one third of these occurred in patients treated with some immunosuppressive therapy.3 The scarcity of presentations in HIV-negative patients and the overlapping features with multiple myeloma present a diagnostic and therapeutic challenge.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Case Report Source Type: research