A case of Cantrell syndrome diagnosed in the first trimester.

A case of Cantrell syndrome diagnosed in the first trimester. Clin Exp Obstet Gynecol. 2016;43(4):612-613 Authors: Delibaş IB, Isaoğlu Ü, Tanriverdi EÇ, Yilmaz M Abstract Here, the authors report a case of Cantrell's syndrome which was diagnosed by ultrasound at 12th week of pregnancy and confirmed by autopsy. Cantrell syndrome/pentalogy is defined as congenital combination of five main distinctive components: defects at the lower part of the sternum, anterior diaphragm, midline supraumbilical abdominal wall, diaphragmatic pericardium, and ectopia cordis. In the present case, in addition to these anomalies, there was cleft palate and cleft lip at the midline. Association of cleft lip and palate with Cantrell's syndrome may be due to the extension of defective migration of mesodennal primordial structures, which is mainly in abdomen and thorax, towards facial structures. Therefore, in prenatal diagnosis facial anomalies should be examined carefully in all cases with Cantrell syndrome. PMID: 29734561 [PubMed]
Source: Clinical and Experimental Obstetrics and Gynecology - Category: OBGYN Tags: Clin Exp Obstet Gynecol Source Type: research