The Production of Ac-225.

The Production of Ac-225.
Curr Radiopharm. 2018 Apr 18;:
Authors: Engle JW
Abstract
The radionuclide 225Ac and its daughter 213Bi are among the most interesting alpha emitters being evaluated for incorporation into targeted therapeutic vectors. Global supply of 225Ac is presently insufficient to meet anticipated clinical demand, but the deficiency has been targeted by many research and development efforts, privately and publicly funded. From more than a decade of these endeavors, no single production technology has emerged as a complete solution. In the foreseeable future, global supply of 225Ac will continue to be sourced from a patchwork of production methods and laboratories with a range of radioisotopic purities and achievable yields.
PMID: 29669509 [PubMed - as supplied by publisher]

Source: Current Radiopharmaceuticals - April 20, 2018 Category: Radiology Tags: Curr Radiopharm Source Type: research