Human Dental Pulp Cells Express Cellular Markers for Inflammation and Hard Tissue Formation in Response to Bacterial Information

Lipopolysaccharide (LPS) is a major component of the outer membranes of gram-negative bacteria associated with deep dental caries and pulpitis. When bacteria invade dentinal tubes and dentin is continually destroyed, tertiary dentin is formed by preexisting odontoblasts. However, the relationship between LPS and tertiary dentin formation remains unclear. We investigated whether LPS stimulation induces the formation of hard tissue in human dental pulp cells (hDPCs).

Source: Journal of Endodontics - April 18, 2018 Category: Dentistry Authors: Akina Sugiuchi, Yousuke Sano, Masahiro Furusawa, Shu Abe, Takashi Muramatsu Tags: Basic Research Source Type: research